BIOOCUS CGT Center
Tianjin Perennial Medical City
World-Class Cell, Gene, and Tissue (CGT) Therapies for Global Patients
As part of the BIOOCUS Global Medical Network, Tianjin Perennial Medical City stands as Northern China’s premier center for personalized oncology and regenerative medicine. This center integrates cutting-edge CAR-T, TIL, NK cell, and stem cell therapies, serving patients from more than 50 countries worldwide.
Since 2016, the center has treated over 1,600 CAR-T patients (as of October 2025), achieving:
● 80–90% initial remission
●40–60% long-term complete remission (CR)
● 95%+ overall response rate (ORR) for hematologic cancers
● 60–92% disease control rate (DCR) for solid tumors
These outcomes are powered by IL-15–enhanced CAR-T technology, which improves tumor infiltration, T-cell survival, and resistance to antigen escape.
Pioneering CGT Therapies with Proven Clinical Results
Comprehensive Therapeutic Portfolio
CAR-T Therapy
l Targets: CD19 / BCMA (hematologic), CLDN18.2 (gastrointestinal), GPC3 (liver/HCC), CEA (lung/NSCLC), B7H3 (glioma), GD2 (neuroblastoma)
l Outcomes: Up to 90% CR for blood cancers and significant disease control across solid tumor types.
TIL Therapy
l Results: 40% ORR and 80% tumor reduction in melanoma patients.
NK Cell & Stem Cell Therapies
l Incorporating ADC drugs, tumor organoids, and radionuclide therapies (Y-90, Lu-177, Ac-225) for personalized precision treatment.
|
Cancer Type |
Target |
Patients |
ORR |
DCR |
Key Outcomes (BIOOCUS Data) |
|
Blood Cancers |
CD19 / BCMA |
~1,000 |
95%+ |
– |
90% CR; 40–60% long-term CR |
|
GI Cancers |
CLDN18.2 |
98 |
38.8% |
91.8% |
mPFS 4.4m; mOS 8.8m |
|
Liver (HCC) |
GPC3 |
32 |
56.6% |
86.7% |
mPFS 13m; mOS 14.6m |
|
Lung (NSCLC) |
CEA |
10 |
55.6% |
88.9% |
1-year OS 77.8% |
|
Glioma (rHGG) |
B7H3 |
39 |
30–40% |
60–70% |
mOS 11–13.6m |
|
Melanoma |
TIL |
12 |
40% |
80% |
80% tumor reduction |
Safety Profile:
Most patients experience only mild CRS; no ICANS or deaths were reported in major clinical studies.
Multidisciplinary Precision Oncology – One-Stop Integrated Care
Tianjin Perennial Medical City
BIOOCUS Tianjin Perennial provides comprehensive, team-based cancer management through a multidisciplinary treatment (MDT) model, combining surgery, interventional therapy, immunotherapy, radiology, and supportive care.
Core Departments and Experts
Surgery & Interventional Oncology: Minimally invasive treatments (nanoknife, cryoablation, RFA, laparoscopy) led by Prof. Liang Han (gastric cancer) and Dr. Li Liming (urologic cancers).
Medical Oncology: Advanced immuno-targeted therapies under Dr. Yao Yaqun, with 40+ years of clinical experience in GI, lung, and breast cancers
Nuclear Medicine: State-of-the-art PET-CT imaging and targeted radionuclide therapy.
Radiotherapy: Equipped with TOMO, Gamma Knife, VMAT, SBRT, and ART systems; BNCT and proton therapy launching soon.
Holistic Care: Integrated TCM, nutritional support, psychotherapy (Dr. Wang Yulu), and reconstructive surgery (Dr. Yin Zhuming).
Facilities & Environment
A 1,000-bed medical ecosystem combining hospital, rehabilitation, and wellness facilities—offering seamless recovery in a green and patient-centered healing environment.
International Patient Excellence – Seamless Global Access
Tianjin Perennial Medical City
The center offers a VIP one-stop service platform designed for international families seeking world-class care in China.
Key Services:
Free AI Consultations – Upload medical records at bioocus.com.
Multilingual Assistance – English, Spanish, and more; 24/7 coordinators available.
Visa & Travel Support – Airport transfers, documentation, and full logistics coordination.
Transparent Billing – No hidden costs; all-inclusive packages available.
Convenient Access – Only 30 minutes from Beijing via high-speed rail.
Long-Term Follow-Up – Remote recovery monitoring and rehabilitation support.
|
Service Area |
BIOOCUS Perennial Advantage |
|
Travel |
Rail hub access + on-site luxury accommodation |
|
Coordination |
24/7 multilingual VIP service |
|
Visa & Insurance |
Full administrative support |
|
Recovery |
Personalized rehabilitation programs |
Elite Medical Team – World-Class Credentials
|
Specialist |
Expertise |
Highlights |
|
Prof. Liang Han |
Gastric Oncology |
National Awards, 550+ papers, collaboration with MD Anderson |
|
Dr. Li Liming |
Prostate & Kidney |
Chief of Tianjin Oncology; “Top Doctor” |
|
Dr. Pan Lekang |
Breast Cancer |
Tokyo MD/PhD; trained at Harvard & ASCO |
|
Dr. Yao Yaqun |
Immuno-Oncology |
40+ years of GI, lung, and breast cancer expertise |
|
+20 More Specialists |
Thoracic, Gynecologic, Plastic Surgery |
Internationally trained, including MD Anderson alumni |
BIOOCUS CGT Center – Tianjin Perennial Medical City
Where Innovation Meets Compassion.
Delivering next-generation immunotherapies and global patient care—from diagnosis to recovery.
Environment, Patient Services, and More
Perennial Tianjin Medical City isn't just about treatment—it's about creating a nurturing, patient-centered environment that makes your healthcare journey comfortable and stress-free. The campus is thoughtfully designed as a green, modern oasis in bustling Tianjin, with spacious, well-lit facilities that blend cutting-edge technology with serene surroundings to promote healing and relaxation. Its prime location near the high-speed rail hub ensures effortless access, whether you're traveling from Beijing, Shanghai, or internationally, reducing travel fatigue and allowing more time for recovery.
Our patient services are tailored to exceed expectations, with multilingual support, personalized care plans, and a focus on transparency—no hidden fees, just clear explanations and options. Enjoy concierge-level assistance, including appointment scheduling, insurance coordination (now including government programs), and family accommodations in on-site hotels with nearly 1,000 rooms across four brands, from luxury to mid-range. For extended stays, the integrated senior care community offers 1,800 beds with full-spectrum med-senior living, including social activities like tea workshops and cultural salons, ensuring a supportive space for all ages. Complementary amenities such as retail spaces, dining options, and wellness programs further enhance your experience, making Perennial Tianjin Medical City not just a hospital, but a holistic haven for health and well-being.
BIOOCUS Medical Group
Oct. 2025