Impi kaWu: Uhlushwa yi-myeloma eminingi
Isiguli uWu, owesilisa oneminyaka engu-71 ubudala, watholakala ene-myeloma eminingi.
Wafuna ukwelashwa e-Biocus International Medical Center ngo-2022 futhi weneliseke kakhulu ngokunakekelwa kwakhe. I-pathology yokuqala yembula okutholwe kwe-MRI ye-lumbar kanye ne-T5T scan, kuhlanganise ne-T10, T11, ne-L1 cone fractures nge-edema yomnkantsha. Ukwengeza, izimpawu ezincane ezingavamile ezingavamile zabonwa emzimbeni we-L2 vertebral. I-biopsy ye-vertebral puncture yaqinisekisa i-plasma cell myeloma. Ukuhlola okwengeziwe kubonise i-plasma ye-prokaryotic ehlanganisa i-46% ye-biopsy yomnkantsha wamathambo, namangqamuzana afakwe ngokungavamile akha i-14% ku-cytometry yokugeleza. I-biopsy ye-bone junction ibonise i-problastoma engu-70%. Ukuhlaziywa kwe-FISH kwembule ukulahlekelwa kwezakhi zofuzo ku-lq21 (CKSIB) naku-1m32 (CDKN2C), kuyilapho ukuhlolwa kwe-FTSH kwakunethemba lokususwa kofuzo lwe-p53, futhi i-ICH yayingenayo kuhlolo lwe-FISH. Ukuxilongwa kokugcina kwakuyi-multiple osteoblastic follipoma (uhlobo lwe-L light chain), nesiteji se-DS eqenjini lesigaba B, isiteji se-ISS se-ISS, kanye nesiteji se-RISS eSigabeni II. Isiguli u-Wu sizwakalise ukubonga ngokwelashwa okuphelele nokuqondene nomuntu siqu okuhlinzekwa yisikhungo sezokwelapha.
Umlando wokwelashwa wangaphambilini:
Ukubonakaliswa komtholampilo kwe-myeloma eminingi kuhlukene, ikakhulukazi okuhlanganisa i-anemia, ubuhlungu bethambo, ukungasebenzi kahle kwezinso, ukutheleleka, ukopha, izimpawu zemizwa, i-hypercalcemia, ne-amyloid stool. Isibhedlela senza ukwelashwa okunamandla okulwa nokutheleleka futhi salungisa i-anemia nama-platelet aphansi. Cishe ngemva kwezinyanga ezingu-2 i-BCMA CAR-T cell infusion, izinkomba zesiguli kancane kancane zabuyela esimweni esijwayelekile, futhi isimo sakhe sasilawulwa. I-Biocus International Medical Centre ibilokhu iqapha isiguli ngokuqhubekayo ukuze iqinisekise ukuzinza okuqhubekayo kwemiphumela yokwelashwa.
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