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Ucwaningo lwakamuva ku-Nature Communications lwembula imininingwane ebalulekile ezindleleni zokusayina zangaphakathi ezilungisa ukuphumelela kokuwohloka kwamaprotheni okuhlosiwe kusetshenziswa ama-PROTAC. Lokhu kutholakala kungavula indlela yokwelashwa okusebenzayo komdlavuza nezinye izifo.

Ukuqinisekisa ukwelashwa okuphephile nokunethezekile kweziguli ze-leukemia kuhilela ukunakekelwa ngokucophelela kwansuku zonke, okuhlanganisa ukukhucululwa kwemvelo, ukuhlanzeka komuntu siqu, ukudla okunomsoco, nokuzivocavoca okufanele. Lo mhlahlandlela unikeza izeluleko ezibalulekile zokunakekelwa kwansuku zonke okusebenzayo ukusekela ukululama.

Ucwaningo lwakamuva lugqamisa ukusebenza kahle nokuphepha kwe-NS7CAR-T cell therapy ekwelapheni i-T-cell acute lymphoblastic leukemia (R/R T-ALL) ebuyele emuva noma eyi-refractory (R/R T-ALL) kanye ne-T-cell lymphoblastic lymphoma (R/R T-LBL). Lokhu kwelashwa kunikeza ithemba elisha ezigulini ezinalezi zinhlobo zomdlavuza ezinolaka.

Ucwaningo lwakamuva lugqamisa imiphumela ethembisayo ye-CD7-targeted chimeric antigen receptor (CAR) T cell therapy ekwelapheni iziguli ezine-T-cell acute lymphoblastic leukemia (T-ALL) ne-T-cell lymphoblastic lymphoma (T-LBL) ebuyele emuva noma ephikisayo.

Umhlangano Waminyaka Yonke Wama-66 we-American Society of Hematology (ASH) uzoba kusukela ngoDisemba 7-10, 2024, e-San Diego Convention Center, ubonisa ucwaningo oluyisisekelo kanye nentuthuko ku-hematology.

I-12th Annual Lu Daopei Hematology Forum izoba ngo-Agasti 23-24, 2024, e-Beijing International Convention Centre. Hlanganyela nathi ukuze uthole izingxoxo ezihlakaniphile kanye nentuthuko yakamuva ku-hematology.

Naphezu kwezinselele eziqhubekayo ekuthuthukisweni kwezimboni nasekuhwebeni, ukulinganiselwa kokwelashwa kwe-CAR-T kubhekwana nendlela entsha ethembisayo: Ukwelashwa kwe-Tumor-Infiltrating Lymphocyte (TIL). Le mpumelelo imemezela inkathi entsha ekulweni nezimila eziqinile.

Ukwelashwa okuguquguqukayo komdlavuza kungase futhi kukwazi ukwelapha nokusetha kabusha amasosha omzimba ukuze anikeze ukuxolelwa kwesikhathi eside noma mhlawumbe ngisho nokwelapha izifo ezithile ezizimele.

Ucwaningo lomtholampilo lwesigaba I se-CD7 CAR-T se-R/R AML olwenziwa yiqembu lika-Daopei Lu okokuqala ngqa e-ASHUmhlangano Waminyaka Yonke wama-65 we-American Society of Hematology (ASH) wabanjwa ungaxhunyiwe ku-inthanethi (San Diego, USA) futhi ku-inthanethi ngo-December 9-12. , 2023.Izazi zethu zenze umbukiso omuhle walokhu...

I-American Society of Hematology (ASH) ingumhlangano wezemfundo ophezulu emkhakheni we-hematology emhlabeni jikelele. Iqiniso lokuthi iSibhedlela iLu Daopei siqokwe njengowokugcina we-ASH iminyaka elandelanayo kukhombisa ngokugcwele impumelelo yaso ezifundweni ze...

Umhlangano Waminyaka Yonke Wama-65 we-American Society of Hematology (ASH) wabanjwa kusukela mhla ziyisi-9 kuya kumhla ziyi-12 kuZibandlela wezi-2023, e-San Diego, e-USA. Njengomcimbi omkhulu wemfundo ye-hematology omkhulu futhi ophelele emhlabeni wonke, uheha izinkulungwane zochwepheshe nezifundiswa ezivela kuyo yonke indawo...