Umdlavuza we-prostate wezinga eliphezulu ohambisana nama-metastases amaningi amathambo-05
Isiguli, owesilisa oneminyaka engu-67 ubudala, kutholakale ukuthi sinomdlavuza we-prostate wezinga eliphezulu ohambisana nama-metastases amaningi amathambo. Ukuxilongwa kokuqala kwabonisa ukuthi isimila sasinolaka kakhulu futhi asikwazanga ukususwa ngokuphelele ngokuhlinzwa. Naphezu kokuthola imisebe kanye nokwelashwa ngamakhemikhali, isimila saqhubeka sisakazekela ezicutshini ezizungezile futhi asabelanga kahle ekwelashweni.
Uma kubhekwa imikhawulo yokwelashwa kwendabuko kanye nesimo sempilo yesiguli, ukhethe ukubamba iqhaza ocwaningweni lomtholampilo lwe-NK (Natural Killer) yokwelashwa kwamaseli. Uhlelo lokwelapha lwaqala ngesifundo sokuqala ngoFebhuwari 2023, kwalandelwa ukwelashwa kwesondlo njalo ezinyangeni eziyisithupha. Iseshini ngayinye yayihilela ukubuyiselwa kwamangqamuzana omzimba ngokufakwa emthanjeni ukuze kuthuthukiswe amasosha omzimba esiguli ekulweni nesimila.
Ngemva kwenkambo yokuqala yokwelashwa kwe-NK cell, isiguli sabika izimpawu zokuqala zokukhululeka kobuhlungu kanye nezinga lempilo elithuthukisiwe. Amaphuzu akhe okusebenza ngokomzimba anda, futhi isimo sakhe sengqondo sabonisa ukuthuthuka okukhulu.
Ukulandela inkambo yesibili yokwelashwa, ukuhlolwa kwe-PET-CT scan kwenziwa. Imiphumela yokuskena ibonise ukuncipha okukhulu komsebenzi we-metabolic kukho kokubili isimila esiyinhloko se-prostate kanye nama-metastases amathambo, izilonda ezithile ezibonisa ukuhlehla okuphelele. Umthwalo wesimila wehliswa ngokuphawulekayo, okuqinisekisa ukusebenza kahle kokwelashwa.
Kuze kube manje, izinga lempilo yesiguli liye laba ngcono kakhulu, futhi izimpawu zaso zilawulwa kahle ngaphandle kwezimpawu zokuphindelela kwesimila sendawo. Uyaqhubeka nokulandelela njalo nokuqapha ukwelashwa ukuze kuqinisekiswe ukusebenza kahle okuqhubekayo kanye nokuthuthukiswa okuqhubekayo kwesimo sakhe.
Isekelwa ukwelapha kwe-NK cell, isimo sesiguli siye saba ngcono ngokuphawulekayo, sinikeza ukwesekwa okuqinile nesikhuthazo ukuze kuqhutshekwe nokuhlolwa nokusetshenziswa kwe-immunotherapy ezigulini ezinomdlavuza wendlala yesinye.
incazelo2