Idabi likaWu: Ukubandezeleka kwi-myeloma ezininzi

Isigulana uWu, indoda eneminyaka engama-71 ubudala, kwafunyaniswa ukuba une-myeloma eninzi.

Wafuna unyango kwi-Biocus International Medical Centre ngo-2022 kwaye waneliseke kakhulu ngokhathalelo lwakhe. I-pathology yokuqala ibonakalise i-lumbar MRI kunye ne-T5T ukufunyaniswa kwe-scan, kubandakanywa i-T10, i-T11, kunye ne-L1 i-cone fractures kunye ne-bone marrow edema. Ukongezelela, iimpawu ezincinci ezingaqhelekanga ezingaqhelekanga zabonwa kumzimba we-L2 we-vertebral. I-vertebral puncture biopsy iqinisekisile i-plasma cell myeloma. Uvavanyo olongezelelweyo lubonise iplasma yeprokaryotic ebandakanya i-46% ye-bone marrow biopsy, kunye neeseli ezixhonywe ngokungaqhelekanga ezenza i-14% kwi-cytometry yokuhamba. I-Bone junction biopsy ibonise i-70% ye-problastoma. Uhlalutyo lwe-FISH lubonakalise ilahleko yemfuza kwi-lq21 (CKSIB) kunye ne-1m32 (CDKN2C), ngelixa uvavanyo lwe-FTSH lwalulungile kwi-p53 yokususwa kwemfuza, kwaye i-ICH yayingalunganga kuvavanyo lwe-FISH. Ukuxilongwa kokugqibela kwakuyi-multiple osteoblastic follipoma (uhlobo lwe-L light chain), kunye ne-DS staging kwiqela le-B, i-ISS staging III, kunye ne-RISS kwi-Stage II. Isigulana uWu uvakalise umbulelo ngonyango olupheleleyo kunye nolomntu ngamnye olunikezelwa liziko lonyango.

Imbali yonyango lwangaphambili:

Izibonakaliso zeklinikhi ze-myeloma ezininzi zihlukeneyo, ngokukodwa kuquka i-anemia, intlungu yethambo, ukungasebenzi kakuhle kwezintso, usulelo, ukopha, iimpawu ze-neurological, i-hypercalcemia, kunye ne-amyloid stools. Isibhedlele senza unyango olunamandla lokulwa nosulelo kunye nokulungisa i-anemia kunye neeplatelet ezisezantsi. Malunga neenyanga ezi-2 emva kokufakwa kweseli ye-BCMA CAR-T, izikhombisi zesigulane ngokuthe ngcembe zabuyela kwimeko yesiqhelo, kwaye imeko yakhe yayilawulwa. I-Biocus International Medical Centre iye yahlala ibeka iliso kwisigulane ukuqinisekisa uzinzo oluzinzileyo lwemiphumo yonyango.