Umhlaza wesibeleko-03
UNkskz. Kwiminyaka emithathu edlulileyo, uye wafumana ukungonwabi kunye nokudumba kumazantsi esisu, kukhatshwa kukuhla komdla wokutya. Ekuhlolweni kwakhe kwisibhedlele sasemzini, kwafunyaniswa ukuba unomhlaza wesibeleko senqanaba lesi-IV. Ngenxa yenqanaba eliphezulu kunye namathumba amaninzi afunyenwe ekuvuleni isisu, ukususwa ngotyando kwakungenakwenzeka, kushiya ichemotherapy njengeyona ndlela ikhethwayo.
Emva kotyando, i-tumor marker CA125 kwiserum yakhe yonyuka ukusuka kwi-1800 U/mL ukuya ngaphezulu kwe-5000 U/mL. I-chemotherapy eqhubekayo ibonise ukusebenza okuncinci, kunye ne-CA125 yenyuka kwakhona ukuya kwi-8000 U / mL kwiinyanga ezintandathu kamva. Oogqirha baxelela intsapho yakhe ukuba ixesha lakhe eliseleyo lilinganiselwe baza bayicebisa ukuba izilungiselele ngokwasengqondweni. Phezu kwako nje ukufunda ubunzulu bemeko yakhe, uNkszn K akazange abonakalise zimpawu zokuphelelwa lithemba. Ngaphambi kokuba alahle ithemba, wayefuna ukuzama unyango lwamajoni omzimba.
Kunyaka ophelileyo, uNkskz. K wenziwa utyando lwakhe lokuqala ukuze kwenziwe isampulu. Emva kweenyanga ezimbini zokwandiswa kwe-ex vivo, ii-TILs zaphinda zabuyiselwa emzimbeni wakhe. Waba nomkhuhlane ngomhla wokutofa, owathi wehla ngosuku olulandelayo, kwaye waziva engcono kakhulu. Ngoku, emva kweenyanga ezintandathu zonyango, amanqanaba akhe e-CA125 aye ahlala engaphantsi kwe-18 U/mL. Uthelekiso lwe-PET-CT lwe-imaging lubonisa ukuba kwi-24 yokuqala ye-metastatic tumors kuwo wonke umzimba wakhe, inye kuphela eseleyo. NgoMatshi walo nyaka, uNksz.
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