I-Optic Nerve Injury-02

I-Stem Cell Therapy ye-Optic Nerve Injury: UMmangaliso wokubuyisela kwakhona ukubona

Kubugcisa bale mihla bezonyango obuhambela phambili ngokukhawuleza, izifo ezininzi ezazikade zibonakala zinganyangeki ngoku zibona ithemba elitsha. Namhlanje, sabelana ngebali elichukumisayo malunga nonyango lwe-mesenchymal stem cell (MSC) lokulimala kwe-optic nerve, indlela yonyango ezisa ithemba elitsha lokubona kwizigulana ezininzi.

Ibali likaMnu Zhang

UMnu. Zhang, oneminyaka engama-47 ubudala, yinjineli ezinikeleyo. Nangona kunjalo, ubomi bakhe batshintsha kakhulu kwiinyanga ezine ezidlulileyo ngenxa yengozi yemoto. Kule ngozi, uMnu. Zhang uye wagcina umonakalo omkhulu kwi-nerve yakhe ye-optic yasekunene, ebangela ukuhla ngokukhawuleza kombono ukuya kukubona ukukhanya. Ngaphandle kokufumana unyango lwemveli nge-steroids kunye namayeza e-neurotrophic, umbono wakhe wabonisa ukuphucuka okuncinci. Le meko yamkhathaza kakhulu yena nentsapho yakhe.

Emva kwengcebiso yomhlobo, uMnu. Zhang wafunda ngonyango olusakhulayo—i-mesenchymal stem cell therapy. Emva kokubonisana okucacileyo noogqirha abakhethekileyo kunye nokuqonda ngokupheleleyo inkqubo yonyango, uMnu. Zhang wagqiba ekubeni azame le ndlela intsha.

Iiseli ze-stem zithathwe kwi-umbilical cord yegazi lamavolontiya anempilo, zihlolwe ngokungqongqo kwaye zandiswa kwinkcubeko ukuze zibe namandla okuvuselela kunye nokulungisa. Ukulawulwa ngenaliti ye-intrathecal kwi-optic nerve sheath, ezi seli ze-stem zaziswa ngokuchanekileyo kwiliso lasekunene likaMnu.

Inkqubo yonyango yenziwa kwindawo eyinyumba ukuze kuqinisekiswe ukhuseleko kunye nokuchaneka kwinqanaba ngalinye. Ngethuba leveki yokuqala emva kokuhlinzwa, uMnu. Zhang wafumana kuphela ukudumba okuncinci kunye nokungahambi kakuhle kwindawo yokutofa, ngaphandle kwezinye iimpawu ezimbi. Nangona kunjalo, ngokumangalisayo, ekupheleni kwenyanga yokuqala emva kokusebenza, uMnumzana uZhang waqala ukubona ukukhanya okuncinci kwaye wayenokuqonda ukukhanya okuqaqambileyo. Olu tshintsho lwamenza wanethemba ngekamva.

Kwiinyanga ezilandelayo, umbono kaMnu. Zhang waphucuka ngokuthe ngcembe. Ngenyanga yesithathu, wayekwazi ukubona iintshukumo zezinto ezinkulu, kwaye iimvavanyo ezinokuthi zibonwe (VEP) zibonise ukubuyiswa okubonakalayo kokusebenza kwe-optic nerve conduction. Ngenyanga yesithandathu, umbono wakhe wasekunene wazinza malunga ne-0.15, emenza ukuba akwazi ukwahlula iifonti ezinkulu kunye neemilo ezilula, ephucula kakhulu umgangatho wobomi bakhe bemihla ngemihla.

Ukuchacha kukaMnu. Zhang akuthethi nje uloyiso lwamayeza anamhlanje kodwa kukwangqina imigudu edibeneyo yabaphandi bezonyango kunye namavolontiya. Iiseli ze-Mesenchymal stem, ngokukhupha izinto ezahlukeneyo zokukhula kunye ne-cytokines, ziququzelele ukuvuselelwa kunye nokubuyiswa kokusebenza kwe-nerve optic eyonakele. Le ndlela yonyango ibonisa amandla amakhulu, inika ithemba kwizigulane ezininzi ezifana noMnu Zhang.