I-melanoma ye-Ocular (ekuqaleni), ilandelwa ngamathumba esibindi se-metastatic-02

Ngo-2021, uNksz Y ngequbuliso wabona into engaqhelekanga kwiliso lakhe lasekunene. Uhlolisiso olucokisekileyo lwabonisa ukuba unemelanoma yamehlo. Ngethamsanqa, yafunyanwa kwangoko kwaye yahlelwa njengenqanaba 1A, kunye ne-2% kuphela yamathuba e-metastasis. Emva kokunyangwa ngeradiotherapy, wayengenawo umhlaza okwexeshana, nangona iindleko yayibubumfama obusisigxina kwiliso elichaphazelekayo.

Noko ke, ngelishwa, elo thumba labuya kunyaka olandelayo laza laqalisa ukukhula ngokukhawuleza. Umfanekiso wabonisa ukuba isibindi sakhe sasisele sinamathumba angaphezu kweshumi anobukhulu obahlukeneyo. Ngenxa yoko, iingcali zacebisa ukuba athathe inxaxheba kulingo lwekliniki lwe-TIL (i-tumor-infiltrating lymphocyte).

Uyise kaNksz Y kunye nomyeni wakhe baqokelela iirekhodi zakhe zonyango kwaye baqhagamshelana noogqirha kulo lonke ilizwe ukuze bafumane ulingo olufanelekileyo lwekliniki, ekugqibeleni bafumana inkqubo yethu. Le ndlela isebenzisa amajoni omzimba ukulwa umhlaza.

Oogqirha ngotyando basusa inxalenye yethumba kwisibindi sikaNkskz. Lo mkhosi mkhulu weeseli emva koko waphinda wabuyiselwa emzimbeni wakhe ukuze enze uhlaselo oluchanekileyo, olunamandla noluzinzileyo kwiiseli zomhlaza.

Ukulinywa kweeseli ze-TIL kuthathe malunga neeveki ezintathu kwaye kufuna iseshoni yonyango enye kuphela. NgoSeptemba 2023, uNksz Y wafumana iveki ye-chemotherapy, i-TIL infusion, kunye ne-IL-2. Olu nyango lunzima lubangele iziphumo ezibi kakhulu, ezibandakanya intlungu edibeneyo, ukuphefumla, iimpawu zesisu, i-rash, kunye nentloko ebuhlungu.

Noko ke, emva kokuba ezi ziphumo bezingalindelekanga zidambile, kwenzeka ummangaliso. Unyango lwe-TIL lubonakale lusebenza kakhulu. Kwisithuba esingangonyaka, phantse onke amathumba kaNkskz. Ngo-2024, oogqirha basusa phantse isiqingatha sesibindi sakhe, kuquka nethumba lokugqibela. Ekuvukeni kwakhe, waxelelwa ukuba akukho zimpawu zokugula ziseleyo emzimbeni wakhe.