Umhlaza wemiphunga yeseli engeyiyo encinci (NSCLC) -02
Isigulana esiyindoda esineminyaka engama-82 ubudala saqala ukuboniswa ekuqaleni kuka-Matshi ka-2023 sinobuthathaka obuqhubekayo, ukulahlekelwa ngumdla wokutya, kunye nokuncipha komzimba malunga neekhilogram ezi-5. Emva kokwamkelwa, iimviwo ezineenkcukacha zenziwe. Isifuba se-CT scan siveze amaqhuqhuva amaninzi kwimiphunga yomibini, eyona inkulu imalunga ne-2.5 cm. Elona qhuqhuva likhulu kwi-apical segment ye-lobe esezantsi yasekunene kunye nelona qhuqhuva likhulu kwi-dorsal segment ye-lobe ephezulu esekhohlo zombini zinemida engacacanga. Emva kwe-chest biopsy kunye novavanyo lwe-pathological, ukufunyaniswa komhlaza wemiphunga we-cell (NSCLC) ongeyena omncinci waqinisekiswa, kunye ne-adenocarcinoma ekhoyo kwi-dorsal segment ye-lobe ephezulu yasekhohlo kunye ne-apical segment ye-lobe esezantsi yasekunene.
Isigulana emva koko safumana irejimeni ye-NK cell immunotherapy. Emva kwenyanga yokuqala yonyango, uviwo olulandelelweyo lubonisa ukuba akukho tshintsho lubalulekileyo kubukhulu bamaqhuqhuva emiphunga, kodwa iimpawu zesigulane ziphuculwe, ngobuthathaka obuncitshisiweyo kunye nokubuya ngokuthe ngcembe kwesidlo. Emva kwenyanga yesibini yonyango, esinye isifuba se-CT scan sibonise umda ocacileyo kunye nokunciphisa okuncinci kubukhulu be-nodule kwi-apical segment ye-lobe esezantsi yasekunene, kunye ne-necrosis eyingxenye echazwe ngakumbi kwi-nodule kwi-dorsal segment incam ephezulu ngasekhohlo. Ukulandela inyanga yesithathu yonyango, isifuba se-CT sibonise ukunciphisa ngakumbi ubungakanani bamaqhuqhuva kwimiphunga yomibini, kunye ne-nodule enkulu ngoku ayidluli kwi-1.5 cm, ukufunxa izilonda ze-pulmonary, kunye nokuphuculwa kwekliniki.
Isishwankathelo, i-NK cell immunotherapy ibonise ukusebenza kakuhle kunye nokunyamezela kwesi sigulane sineminyaka engama-82 ubudala kunye ne-NSCLC, kunye nokunciphisa okubonakalayo kwizilonda zemiphunga kunye nokuphuculwa okukhulu kwimeko yesigulana sonke. Ukulandelela kunye nezicwangciso zonyango ezongezelelweyo ziya kuqhubeka ukubeka esweni ukuqhubela phambili kwesifo kunye nemiphumo yonyango.
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