Iindaba
Iziphumo ezithembisayo zeCD7 CAR-T Therapy edityaniswe kunye noTshintsho lweSibini kwi-Relapsed T-ALL/LBL Patients
Uphononongo lwakutsha nje luqaqambisa ukusebenza konyango lwe-CD7 CAR-T olulandelwa lulwesibini lwe-allogeneic hematopoietic stem cell transplantation (HSCT) kwizigulane ezine-T-cell acute lymphoblastic leukemia (T-ALL) kunye ne-lymphoblastic lymphoma (LBL), ebonisa amandla amakhulu ukufikelela kwi-minimal residual disease (MRD)-negative uxolelo olupheleleyo.
Ukusebenza kwexesha elide kweCD19 CAR T-Cell Therapy kuNyango oluBuyelweyo/ oluRefractory Acute Lymphoblastic Leukemia
Uphononongo olusisiseko lubonisa impumelelo yexesha elide yeCD19 CAR T-cell therapy ekunyangeni izigulane ezine-relapsed/refractory acute lymphoblastic leukemia (YONKE) ilandela i-allogeneic hematopoietic stem cell transplantation, enika ithemba elitsha kwi-hematology.
I-Bioocus iqhubela phambili kwi-Frontier kuNyango lwaBantwana lwe-Acute Lymphoblastic Leukemia
I-Bioocus iphambili ekuphuhliseni isizukulwana esilandelayo zonyango lwe-CAR-T. Upapasho lwakutsha nje lukaGqr Chunrong Tong kunye neqela lakhe kwiSibhedlele saseLu Daopei lugxininisa ukuqhubela phambili okubalulekileyo kunye nemingeni ekusetyenzisweni kwezonyango ze-CD19 CAR-T zesizukulwana sesibini kwizigulana zabantwana, ebonisa ukuzibophelela kuka-Bioocus kunyango lomhlaza.
Ubuvulindlela Unyango lwe-CAR-T kwi-B-cell Acute Lymphoblastic Leukemia ibonisa ukusebenza ngendlela engazange ibonwe ngaphambili
Uphononongo olusisiseko lubonisa ukusebenza okuphawulekayo kwe-CAR-T yonyango lweseli ekuphatheni i-B-cell Acute Lymphoblastic Leukemia (B-ALL). Uphando, olubandakanya intsebenziswano ne-BIOOCUS kunye neSibhedlele saseLu Daopei, lubonisa ukuqhubela phambili okubonakalayo, ukuseka unyango njengendlela yonyango ebalulekileyo.
UNyango lweeSeli ze-CAR-T ezintsha luguqula unyango lwe-B Cell Malignancies
Abaphandi abavela kwiSibhedlele saseLu Daopei kunye nabadibanisi bamazwe ngamazwe baphonononga iindlela zonyango ze-CAR-T zeseli, ezinika ithemba kwizigulane ezine-B cell malignancies. Olu phononongo luqaqambisa ukuqhubela phambili kuyilo kunye nokusetyenziswa, lubonisa iziphumo ezithembisayo kunye nokubanakho kwezinto ezintsha ezizayo.
Ukomelezwa kokuSebenza kwe-Antitumor ye-4-1BB-Isekelwe kwi-CD19 ye-CAR-T yeeSeli ekuNyangweni kwe-B-ALL
Uphononongo lwamva nje lweklinikhi lubonisa ukuba iiseli ze-CD19 ze-CAR-T ezisekelwe kwi-4-1BB zibonisa ukusebenza kakuhle kwe-antitumor xa kuthelekiswa neeseli ze-CD28 ezisekelwe kwi-CAR-T ekuphatheni i-B cell acute lymphoblastic leukemia (r / r B-ALL) ebuyiselweyo okanye i-refractory.
Unyango lwe-CD19 CAR-T lweSibhedlele saseLu Daopei lubonisa iziphumo ezithembisayo kwi-B-ALL izigulana
Uphononongo lwakutsha nje kwiSibhedlele sase-Lu Daopei lubonise ukusebenza okuphezulu kunye nokhuseleko lwedosi ephantsi yonyango lweseli ye-CD19 CAR-T ekunyangeni izigulane ezi-acute lymphoblastic leukemia (B-ALL) ezichasayo okanye ezibuyele umva. Uphando, olubandakanya izigulane ze-51, lubonise izinga elimangalisayo lokuxolelwa okupheleleyo kunye nemiphumo emibi encinci.
Isicwangciso soMkhuseli weNoveli siphucula uKhuseleko kunye nokusebenza ngokuFanelekileyo koNyango lwe-CAR-T kwi-Acute B Cell Leukemia
Isibhedlele saseLu Daopei kunye ne-Hebei Senlang Biotechnology babhengeze iziphumo ezithembisayo kuphononongo lwabo lwakutsha nje malunga nokhuseleko kunye nokusebenza ngempumelelo konyango lwe-CAR-T lwe-acute B cell leukemia. Le ntsebenziswano ibalaselisa ukubanakho kwenoveli yoyilo lweeseli zeCAR-T ukomeleza iziphumo zesigulana.
Uphononongo oluPhumeleleyo lubonisa uKhuseleko kunye nokusebenza ngokuSebenza koNyango lwe-CAR-T kuNyango lwe-B-Cell Malignancies
Uphononongo olutsha olukhokelwa nguDkt Zhi-tao Ying ovela kwiSibhedlele somhlaza weYunivesithi yasePeking uye wabonisa ukhuseleko kunye nokusebenza kakuhle kwe-IM19 CAR-T yonyango lweseli ekuphatheni i-B-cell hematologic malignancies. Ipapashwe kwiIjenali yaseTshayina yamachiza amatsha, uphando lubika ukuba i-11 kwizigulane ze-12 zafumana ukuxolelwa okupheleleyo ngaphandle kwemiphumo emibi kakhulu, ebonisa amandla e-IM19 njengendlela yonyango ethembisayo kwizigulane ezinezinye iindlela ezilinganiselweyo.
Ukuqhubela phambili kwiNkcazo yoMbulali weNdalo (NK) kwiiseli ezingaphezu kweminyaka eyi-50
Kwiminyaka engamashumi amahlanu edlulileyo, uphando kwi-Natural Killer (NK) iiseli ziye zaguqula ukuqonda kwethu ukugonywa kwemvelo, enikezela ngeendlela ezintsha ezithembisayo zomhlaza kunye nonyango lwentsholongwane.
ULawulo lweGazi loNyango lweKlinikhi kunye noQeqesho lweTekhnoloji yoTshintsho oluBanjelwe kwiSibhedlele saseYanda Ludaopei
UQeqesho loNyaka lwama-2024 loLawulo lweGazi leKlinikhi kunye neTekhnoloji yoTshintsho kwiSixeko saseSanhe lubanjwe ngempumelelo kwiSibhedlele saseYanda Ludaopei. Esi siganeko sijolise ekuphuculeni ulawulo lwegazi lweklinikhi kunye nokhuseleko lotofelo-gazi ngokusebenzisa iiseshoni zoqeqesho ezibanzi ezizinyaswe ngabasebenzi bezempilo abangaphezu kwe-100 abavela kumaziko ahlukeneyo ezonyango.
Ukuphumelela kwiZifo eziZimelayo zaBantwana: Unyango lweeseli ze-CAR-T Unyanga isigulana seLupus
Uphononongo olungoovulindlela kwiSibhedlele seYunivesithi yase-Erlangen ngempumelelo yanyanga intombazana eneminyaka eli-16 ubudala ene-systemic lupus erythematosus (SLE) enzima esebenzisa unyango lweseli ye-CAR-T. Oku kuphawula ukusetyenziswa kokuqala kolu nyango lwe-lupus yabantwana, enika ithemba elitsha kubantwana abanezifo ezizimelayo.