I-Metastatic melanoma-04

Isigulana uMnu. Li, indoda eneminyaka engama-45 ubudala, waqala ukufumana intlungu eqhubekayo yesisu kunye nokulahlekelwa kwesisindo ekuqaleni kuka-Matshi 2022. Uviwo olulandelayo kwisibhedlele sendawo lwakhokelela ekubeni axilongwe ngo-Aprili 2022 nge-melanoma ye-metastatic. Phezu kwako nje ukuzama iindlela ezininzi zonyango oluqhelekileyo, oluquka utyando, unyango ngeradiotherapy nonyango lwechemotherapy, imeko yakhe yaqhubeka isiba mandundu, njengoko amathumba asasazeka esibindini nakwimiphunga yakhe.

Emva kwemizamo engaphumelelanga kunye nonyango oluqhelekileyo, uMnu. Li wafuna iindlela zonyango ezizezinye ngoDisemba 2022 kwiingcebiso zonyango. Emva kokubonisana ngokubanzi kunye nophando, wagqiba ekubeni azame i-immunotherapy entsha ebizwa ngokuba yi-Tumor-Infiltrating Lymphocyte (TILs) unyango.

Inkqubo yoNyango lwe-TILs:

1. Ukutsalwa kweSampuli yethumba: NgoJanuwari ka-2023, uMnu.

2. Ukwandiswa kweLymphocyte: Kwibhubhoratri, abaphandi bahlukanisa i-Tumor-Infiltrating Lymphocytes (TILs) kwisampuli ye-tumor ekhutshwe. Ezi lymphocytes zandiswa amaxesha amaninzi kwi-vitro ukufikelela ubungakanani obufunekayo kunyango.

3. Ukulungiselela i-Chemotherapy: Ngaphambi kokufakwa kweeseli ze-TILs, uMnu. Li wafumana i-chemotherapy ixesha lokunciphisa inani le-lymphocytes ekhoyo emzimbeni wakhe, okwenza indawo yeeseli ze-TILs ezisanda kufakwa.

4. I-TILs Cell Infusion: NgoMatshi ka-2023, iiseli ezandisiweyo ze-TILs zabuyiselwa kumzimba kaMnu. Li nge-intravenous infusion.

5. Unyango oluxhasayo: Ukuphucula umsebenzi we-TILs, uMnu. Li naye wafumana ii-injection ezininzi ze-Interleukin-2 (IL-2).

Kwiinyanga ezilandela unyango, imeko kaMnu. Li yaphucuka kakhulu. Amathumba ancipha ngokuphawulekayo, kwaye izilonda zemetastatic zabonisa ukukhululeka kancinci. Ukulandelelwa ngoJuni ka-2023 kwatyhila ukunyamalala ngokupheleleyo kwamathumba esibindini nakwimiphunga. Impilo kaMnu. Li yaya isiba bhetele ngokuthe ngcembe, ubunzima bakhe babuya, zaza iintlungu zesisu zehla.

"Xa ndafunda ngemeko yam, kwavakala ngathi ihlabathi liphela liyawohloka. Emva kokufumana unyango oluninzi olungasebenziyo, ndaphantse ndaphelelwa lithemba. Ngethamsanqa, ndadibana nonyango lwe-TILs, olungazange lusindise ubomi bam kuphela kodwa lwabuyisela ithemba lam ngekamva. .Ndiyabulela kubo bonke oogqirha kunye nabaphandi abandincedileyo Yimizamo yenu ethe yandinika ingqesho entsha ebomini.