Isigaba somhlaza we-Endometrial IVB-04
Isigulana yayingowasetyhini oneminyaka engama-55 ubudala, kwaye i-histopathology ye-biopsy yaqinisekisa ukufunyaniswa kwenqanaba lomhlaza we-endometrial owahlulwe kakubi we-IVB.
Ukwahlula okuphantsi kunye nobubi obuphezulu. Ithumba lakhe liye lakhula yaye lalingenakushenxiswa ngokupheleleyo ngotyando. Uvavanyo olongezelelweyo lubonise ukuba izigulane ziye zanciphisa umlinganiselo we-lymphocyte kunye nokubala kunye nomsebenzi ophantsi kakhulu we-NK cell. Ayikwazanga ukunyamezela iziphumo ezibi, wayiyeka ichemotherapy waza wathatha inxaxheba kulingo lwezonyango lweeseli zentambo ze-NK.
Esi sigulana safumana unyango lokuqala ngoFebruwari 2021 kwaye okwesibini kwiinyanga ezi-6 kamva. Kwiintsuku ezi-4 ezilandelelanayo, i-infusion yemihla ngemihla ye-intravenous kunye ne-immunophenotyping yenziwa ngaphambi nangemva komjikelezo ngamnye wonyango.
Emva kwekhosi yokuqala ye-immunotherapy kwintambo yegazi NK iiseli, isigulane siphumelele ukuxolelwa ngokuyinxenye. Amandla akhe omzimba, ukutya, kunye nomgangatho wokulala zonke ziphucukile.
Emva kwekhosi yesibini yonyango, umphandi wenza i-PET-CT scan. I-scan ibonise ukunciphisa ubungakanani obufanelekileyo be-uterine hypermetabolic mass kunye nokunciphisa okukhulu kwimetabolism ye-uterine kunye nomthamo xa kuthelekiswa nangaphambi kokuba unyango. Nangona i-femoral head mass right kunye ne-10th kunye ne-11th rib metastasis yayingatshintshi, i-metabolism ye-bone metastases yayiqhelekile. Iimetastases ezininzi ze-lymph node entanyeni, i-mediastinum, i-retroperitoneum, kunye ne-pelvis nazo zanyamalala.
Emva kweekhosi ezimbini, umgangatho wesimo somzimba wehla ukusuka kwi-3 ukuya kwi-1 kwaye umgangatho wobomi uphuculwe kakhulu.
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