Isishwankathelo esiBanzi seGroundbreaking Leukemia Treatment
Iimpawu zeCAR-T
●I-B-cell acute lymphoblastic leukemia
●I-myeloma ezininzi
●I-lymphocytic leukemia engapheliyo
●I-Non-Hodgkin lymphoma
●Ukusasaza i-B-cell lymphoma enkulu
●I-SLE (Systemic Lupus Erythematosus)
●I-Myasthenia gravis
●Ezinye izifo ze-autoimmune
Ukusebenza kakuhle kwekliniki ye-CAR-T
Iimpawu zeCD19+20CAR-T:Izigulane ezine-B-cell non Hodgkin's lymphoma
Ireyithi ye-CR yenyanga enye | Ireyithi ye-PR yenyanga enye | Inyanga enye OKANYE izinga | CRS≥3 | CRES≥3 |
71.95% (59/82) | 25.6 (21/82) | 97.55 (80/82) | 12.19% (10/82) | 0 |
Iimpawu zeCD19+22CAR-T:Unyango lwe-CD19 ebuyileyo kunye ne-refractory acute B-lymphocytic leukemia izigulane
Ireyithi ye-CR yenyanga enye | Ireyithi ye-PR yenyanga enye | Inyanga enye OKANYE izinga | CRS≥3 | CRES≥3 |
92.1% (35/38) | 7.9% (3/38) | 100% (38/38) | 15.79% (6/38) | 0 |
Iimpawu ze BCMACAR-T:Unyango lwe-myeloma ephindaphindiweyo kunye ne-refractory
Ireyithi ye-CR yenyanga enye | Ireyithi ye-PR yenyanga enye | Inyanga enye OKANYE izinga | CRS≥3 | CRES≥3 |
72.41% (21/29) | 27.59% (8/29) | 100% (29/29) | 6.9% (2/29) | 0 |
Izinto Eziluncedo Zethu
● Unyango Lomntu: Unyango ngalunye lwe-CAR-T lulungiselelwe isigulane, luqinisekisa iziphumo zonyango ezijoliswe kakhulu kunye nezisebenzayo.
● Iinketho ezahlukeneyo zokuJonga: Ngoluhlu olubanzi lwee-antigens ezijoliswe kuyo, kubandakanywa i-CD7, i-CD19, i-CD20, i-CD22, kunye ne-BCMA, iimveliso zethu ze-CAR-T zibonelela ngokungafaniyo okungafaniyo ekuphatheni izifo ezahlukeneyo ze-hematological kunye nezifo ezizimele.
● Impumelelo yeklinikhi eqinisekisiweyo: Unyango lwethu lwe-CAR-T lubonise ukusebenza okungaqhelekanga kuzo zonke iimeko ezininzi zeklinikhi, kunye namazinga achukumisayo oxolelo kunye neeprofayili zokhuseleko, ukuqinisa isikhundla sethu njengenkokeli kunyango lomzimba.
● Iindleko eziphezulu-Ngempumelelo: Sinikezela ngomphetho okhuphisanayo nonyango olukumgangatho ophezulu ngamaxabiso afikelelekayo xa kuthelekiswa nezinye iimveliso zeCAR-T kwimarike.
● Itekhnoloji yokusika: Ukusetyenziswa kwenkqubela phambili yamva nje kubunjineli bemfuza, unyango lwethu lwe-CAR-T lubandakanya ikamva lomhlaza kunye nonyango lwe-autoimmune disease.
● INkxaso yoNyango lweNgcali: Iqela lethu elinamava leeklinikhi kunye nabaphandi banikezela ngononophelo olubanzi ukusuka ekudibaneni kokuqala ngolawulo lonyango kunye nokulandelwa.
Iiseli ze-CAR-T ngoku ziyaziwa ngokubanzi ngokusebenza kwazo kwizigulana ezingakhange ziphendule kunyango lwesintu olufana nechemotherapy okanye ithambo lotyando. Uluntu lwezonyango lwehlabathi luvuma amandla aphantsi onyango lwe-CAR-T ekuguquleni iziphumo zesigulane.
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