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Unyango lweGene olutsha lubonelela ngeThemba elitsha kwiSickle Cell kunye nezigulana zeThalassemia

Unyango lweGene olutsha lubonelela ngeThemba elitsha kwiSickle Cell kunye nezigulana zeThalassemia
I-FUCASO: Unyango lwe-BCMA CAR-T yoMntu ngokuPheleleyo ngokuSebenza ngoKusebenza kunye noKhuseleko.

I-FUCASO: Unyango lwe-BCMA CAR-T yoMntu ngokuPheleleyo ngokuSebenza ngoKusebenza kunye noKhuseleko.
I-Optic Nerve Injury-03

I-Optic Nerve Injury-03
I-Optic Nerve Injury-02

I-Optic Nerve Injury-02
I-Optic Nerve Injury-01

I-Optic Nerve Injury-01
I-Metastatic melanoma-04

I-Metastatic melanoma-04
Umhlaza wesibeleko-03

Umhlaza wesibeleko-03
I-melanoma ye-Ocular (ekuqaleni), ilandelwa ngamathumba esibindi se-metastatic-02

I-melanoma ye-Ocular (ekuqaleni), ilandelwa ngamathumba esibindi se-metastatic-02
Inqanaba eliphezulu le-IV lomhlaza we-colorectal-01

Inqanaba eliphezulu le-IV lomhlaza we-colorectal-01
Umhlaza we-prostate womgangatho ophezulu uhamba kunye ne-bone metastases-05

Umhlaza we-prostate womgangatho ophezulu uhamba kunye ne-bone metastases-05
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Inqanaba eliphezulu le-IV lomhlaza we-colorectal-01

Isigulana:XXX

Isini: Indoda

Ubudala: iminyaka engama-45 ubudala

Ubuzwe:IsiTshayina

Uxilongo: Inqanaba eliphezulu le-IV lomhlaza womlomo

    Qhagamshelana nathi

    Isigulane yindoda eneminyaka engama-45 ubudala eyafunyaniswa nenqanaba eliphezulu le-IV lomhlaza we-colorectal ngoJanuwari 2023. Ekuqaleni, oogqirha bacebisa ikhosi epheleleyo ye-chemoradiotherapy. Nangona kunjalo, ngenxa yokuchaphazeleka kakhulu kwe-neurotoxicity, kubandakanya i-paresthesia kunye nobuthathaka belungu emva kwechemotherapy, isigulana sagqiba kwelokuba siyeke ukuqhubeka nonyango lwe-chemoradio.


    Ngethamsanqa, isigulana sadibana neendlela zokugaya kulingo lwezonyango lwe-autologous tumor-infiltrating lymphocyte (TIL) kwaye wakhetha ukuthatha inxaxheba kulingo. Ekuqaleni kuka-Epreli ka-2023, isigulana safumana ukufakelwa kweseli ye-TIL kwaye emva koko senziwa i-PD-1 monoclonal antibody immunotherapy ngokweprothokholi yolingo kwiinyanga ezimbini ezizayo.


    Emva kokunyanga, isigulane sichaze ukuphuculwa okuphawulekayo kwiimpawu zesisu kunye nokubuyiswa kakuhle komsebenzi wamathumbu. I-CT scan yokuqala yomzimba ogcweleyo emva kokuba i-infusion ibonise ukunciphisa umthwalo we-tumor, ngokukodwa kwisibindi kunye nezilonda ze-peritoneal. Njengoko unyango lwaluqhubeka, ukuqina komzimba wesigulana kunye nomgangatho wobomi ngokuthe ngcembe waphucuka.


    Ngenyanga yesithathu yonyango, izikena zokulandelela zabonisa ukuqhubeka kokuncipha kwethumba. I-PET-CT scan yomzimba wonke ibonise ukunciphisa kakhulu umsebenzi we-metabolic kwizilonda ze-metastatic, kunye nezilonda eziphela ngokupheleleyo. Ukuza kuthi ga ngoku, ulandelelwano lwenyanga lubonisa ukuba ithumba lihlala lizinzile kungekho zilonda zitsha okanye iimpawu zokuphindaphinda.

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