E hasanya B-cell lymphoma (DBCL), NOS, GCB subtype, tsamaiso ea methapo ea mantlha ea lymphoma-01.

Ka December 2019, Monghali Wang, mosuoe ea tsoang Leboea-bochabela ho China, o ile a qala ho tšoaroa ke hlooho. Ka la 19 Tšitoe, 2019, liteko tsa tlhahlobo ea mafu li senotse tse latelang: PET-CT e bonts'itse moriti o teteaneng o nang le metabolism e eketsehileng ea FDG karolong e ka pele ea lobe le corpus callosum lengole (hoo e ka bang 3.4 * 1.9 cm, SUVmax = 34.4). Biopsy le immunohistochemistry li netefalitse hore li na le mofuta o moholo oa B-cell lymphoma (DLBCL, NOS, GCB subtype), e nang le immunophenotype e bonts'ang Ki67(50%+), CD19(+), CD20(+), PAX5(+), CD79(+), MUM1(+), BCL(+), CD10(-/+), CD2(minor+). Tlhahlobo ea mokelikeli oa cerebrospinal e senotse 6% ea lisele tse immature lymphoid tse nang le phapang ea morphological. Tlhahlobo e ne e le ea mantlha ea methapo ea methapo ea lymphoma (DBCL, GCB subtype).

Ka mor'a ho etsa lipatlisiso tsa mekhoa ea phekolo Inthaneteng, Monghali Wang o ile a ithuta ka bokhoni ba immunotherapy ea Lu Dao Pei Hospital 'me hang-hang a batla tsebo ea bona. Ka mor'a litlhahlobo tse feletseng tsa 'mele le tlhahlobo e hlokolosi ea sehlopha sa litsebi tsa sepetlele, ho ile ha etsoa qeto ea hore Monghali Wang o tla kenya letsoho tekong ea bongaka bakeng sa phekolo ea CART, haholo-holo a sebelisa CD19 CART cell. O ile a fumana infusion ea lisele tsa CD19 CAR-T ea autologous ka la 24 Mmesa, 2023. Ka la 30 Phupu, 2023, o ile a hlahlojoa hore o fumane tšoarelo e felletseng (CR) mme esale a khutlela bophelong bo tloaelehileng.