Mokhahlelo o tsoetseng pele oa IV oa mofets'e oa colorectal-01
Mokuli ke monna ea lilemo li 45 ea ileng a fumanoa a e-na le kankere e tsoetseng pele ea IV ka January 2023. Qalong, lingaka li ile tsa khothalletsa mokhoa o feletseng oa chemoradiotherapy. Leha ho le joalo, ka lebaka la ts'oaetso e matla ea neurotoxicity, ho kopanyelletsa le paresthesia le bofokoli ba maoto ka mor'a phekolo ea lik'hemik'hale, mokuli o ile a etsa qeto ea ho khaotsa ho sebelisa chemoradiotherapy.
Ka lehlohonolo, mokuli o ile a kopana le litekanyetso tsa ho hira bakeng sa teko ea tleliniki ea phekolo ea autologous tumor-infiltrating lymphocyte (TIL) 'me a khetha ka mafolofolo ho kenya letsoho tekong. Mathoasong a Mmesa 2023, mokuli o ile a fumana infusion ea sele ea TIL mme kamora moo a fuoa PD-1 monoclonal antibody immunotherapy ho latela protocol ea liteko likhoeling tse peli tse tlang.
Ka mor'a phekolo, mokuli o ile a tlaleha ntlafatso e kholo ea matšoao a mala le ho hlaphoheloa hantle ha mala. Tlhahlobo ea pele ea 'mele e feletseng ea CT ka mor'a hore e tšeloe e bontšitse ho fokotseha ha moroalo oa hlahala, haholo-holo sebeteng le peritoneal diso. Ha phekolo e ntse e tsoela pele, ho phela hantle ’meleng le boleng ba bophelo ba mokuli li ile tsa ntlafala butle-butle.
Khoeling ea boraro ea kalafo, litlhahlobo tse latelang li ile tsa bontša hore hlahala e ntse e fokotseha. Tlhahlobo ea PET-CT ea 'mele oohle e senotse tšebetso ea metabolism e fokotsehileng haholo maqeba a metastase, 'me liso tse ling li nyamela ka ho felletseng. Ho tloha joale, litlhahlobo tsa khoeli le khoeli li bontša hore hlahala e ntse e tsitsitse ho se na maqeba a macha kapa matšoao a ho ipheta.
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