Acute Lymphoblastic Leukemia(T-ALL)-09

Moithuti oa univesithi ea bitsoang Mengmeng ea tsoang Yanjiao, Guizhou, o ile a fumana phekolo e sebetsang Sepetleleng sa Ludaopei.

Mengmeng, mosali, ea lilemo li 21, o hlahisitse tleliniki ea rona ea bakuli ka la 22 Phuptjane 2021, ka mokhathala o sa khaotseng. Teko ea tloaelo ea mali e bonts'itse WBC 479×10^9/L. Litlhahlobo tse ling tsa moko oa masapo li netefalitse acute lymphoblastic leukemia (T-cell subtype). O ile a tšoaroa ka makhetlo a mabeli a phekolo ea lik'hemik'hale, empa leukemia e ile ea lula e sa arabele, 'me MRD (lefu le fokolang la masala) e le 56.01%, hape o ne a e-na le karolo ea tsamaiso ea methapo ea methapo ea mali.

Ka la 13 Phato, li-lymphocyte tsa autologous li ile tsa bokelloa 'me tsa fuoa chemotherapy. Ka la 30 Phato, Mengmeng o ile a fuoa tšelo ea lisele tsa CD7 CAR-T. Libeke tse peli ka mor'a ho tšeloa, tlhahlobo ea moko oa masapo e ile ea bontša ho phomola ka ho feletseng, ho se tsotelle ha MRD, le ho laola leukemia ea tsamaiso ea methapo ea bohareng. O bile le karabelo ea sehlopha sa 1 sa cytokine release syndrome (CRS) ntle le karabelo e mpe ea tsamaiso ea methapo.