Acute Lymphoblastic Leukemia(T-ALL)-08

Yesheng oa Fujian o itse, "Haeba ke ne ke tsebile ka CAR-T e Ludaopei, nka be ke tlile pejana."

Ka September 2017, Yesheng o ile a hlahisa makhopho a sefahleho, a ileng a ata butle-butle 'me a kopana le li-patches. Ka la 28 Hlakola, 2018, tlhahlobo ea moko oa masapo e netefalitse "acute T-cell lymphoblastic leukemia" ka mor'a lithupelo tse ngata tsa chemotherapy, ka tlhahlobo ea nakoana e fosahetseng. Meriana eohle e ile ea emisoa ka Phuptjane 2019.

Ka Mots'eanong 2021, Yesheng o ile a hlahisa bongata sebakeng sa molomo-pharyngeal le li-lymph nodes tsa molala tse atolositsoeng. Tlhahlobo e ncha ea moko oa masapo e netefalitse ho khutlela mokhoeng o felletseng oa leukemia. Ka la 28 Motšeanong, Yesheng o ile a isoa Lefapheng la Bobeli la Hematology la Sepetlele sa Ludaopei bakeng sa ho amoheloa. Ka mor'a litlhahlobo tse feletseng, tlhahlobo e ile ea ntlafatsoa ho "acute leukemia (T/myeloid biphenotypic)."

Modikoloho o mong wa chemotherapy ha o a ka wa etsa hore moko wa lesapo o phomole. Ka la 27 Phupu, Yesheng o ile a amohela infusion ea lisele tsa CD7 CAR-T, e lateloang ke chemotherapy e kopantsoeng le autologous CD7 CAR-T cell therapy. Matsatsi a leshome le metso e mehlano ka mor'a ho tšeloa, tlhahlobo ea moko oa masapo e bontšitse lefu le salileng le lebe, le nang le karabelo ea 1 cytokine release syndrome (CRS) 'me ha ho na tsamaiso ea methapo ea bohareng.