Nidaamka Lupus Erythematosus (SLE) -01

Xiaohuan oo 24 jir ah waxa uu jaamacad ka baranayay cilmiga caafimaadka muddo saddex sano ah,waxana uu la ildaran yahay nidaamka lupus erythematosus (SLE) ku dhawaad ​​10 sano. "Waxaa la igu sheegay 10 jir, dhakhtarkuna waxa uu sheegay in ay aad u adkeyd in la daweeyo, in aan dawo ku xakameyn karo oo kaliya," Xiaohuan ayaa yiri isagoo dhoola cadeynaya. Tobankii sano ee la soo dhaafay, waxay ku qasbanaatay inay aado baaritaanno bille ah iyo dawooyin, waxayna qaadatay daawaynta hoormoonka, daawaynta difaaca jirka, iyo daawaynta noolaha, laakiin midna waxtar uma yeelan. Waxay u adkaysatay timo daataan aad u daran, finan badan, qandho badan oo soo noqnoqda, iyo xanuun baahsan.

Ka dib baaritaanno horudhac ah oo kala duwan, Xiaohuan wuxuu la kulmay dhammaan shuruudaha daawaynta CAR-T ee SLE. Koox khabiiro ah ayaa si taxadar leh u dejiyay qorshe daawayn oo ku salaysan xaaladeeda si taxadar lehna loogu diyaariyay habka ururinta unugyada. 28-kii Maarso, ururinta unugyada mononuclear-ka ayaa bilaabmay. 22-kii Abriil, waxay bilowday lymphodepleting chemotherapy. Abriil 28-keedii, unugyada ayaa dib loo galiyay. 20 milyan oo CAR ah oo unugyo T ah oo wax laga beddelay ayaa si tartiib ah loogu geliyey xididdada Xiaohuan, iyaga oo si toos ah u beegsanaya unugyada lupus B, iyaga oo bilaabaya "weerar sax ah, mid mid u jebiya" dagaalka.

Juun 4teedii, maalintii 38aad ee faleebada ka dib, Xiaohuan wuxuu ku noqday cisbitaalka si uu ula socdo. Natiijooyinka baaritaanku waxay muujiyeen in dhammaan tilmaamayaasha muhiimka ah ay hoos ugu dhaceen heerarka caadiga ah. "Uma baahni dawooyinka hoormoonka; waxay dareemeysaa in noloshu ay hadda bilaabatay," Xiaohuan ayaa si farxad leh u tiri.