Ocular melanoma (pakutanga), inoteverwa nemetastatic chiropa tumors-02
Muna 2021, Mai Y vakaerekana vaona kusajairika mukuona kweziso ravo rekurudyi. Kuongororwa kwakadzama kwakaratidza kuti aive neocular melanoma. Neraki, yakaonekwa nekukurumidza uye yakarongedzerwa sedanho 1A, iine chete 2% mukana wemetastasis. Pashure pokurapwa neradiotherapy, akanga asina kenza kwenguva pfupi, kunyange zvazvo mutengo wacho wakanga uri upofu hwechigarire muziso rakanga rabatwa.
Zvisinei, zvinosuruvarisa kuti bundu racho rakadzoka gore rakatevera racho ndokutanga kufambira mberi nokukurumidza. Kufungidzira kwakaratidza kuti chiropa chake chaitova nemamota anopfuura gumi ehukuru hwakasiyana. Nekuda kweizvozvo, nyanzvi dzakakurudzira kuti atore chikamu muchirongwa chekiriniki cheTIL (tumor-infiltrating lymphocyte).
Baba vaMs Y nemurume vakaunganidza zvinyorwa zvavo zvekurapa uye vakasangana navanachiremba munyika yose kuti vawane muedzo wekiriniki wakakodzera, pakupedzisira vakawana purogiramu yedu. Nzira iyi inoshandisa masoja emuviri kurwisa gomarara.
Vanachiremba vakavhiya chikamu chebundu kubva pachiropa chaMs. Y, masero emhondi ega eT kubva pachiri, ndokuawedzera kusvika pamabhiriyoni gumi kusvika ku150, vachigadzira uto remasero eclone. Iri mauto makuru aya akabva adzoserwa mumuviri wake kuti aite kurwisa chaiko, kwakasimba, uye kwakasimba pamaseru egomarara.
Kurimwa kwemasero eTIL kwakatora mavhiki matatu uye kwaida chikamu chimwe chete chekurapa. MunaGunyana 2023, Ms. Y vakaita svondo rechemotherapy, TIL infusion, uye IL-2. Kurapwa kwakanyanya uku kwakakonzera mhedzisiro yakaoma, kusanganisira kurwadziwa kwemajoini, kusagadzikana kwekufema, zviratidzo zvedumbu, kuputika, uye kutemwa nemusoro kwakanyanya.
Zvisinei, mushure mokunge migumisiro iyi yapera, chishamiso chakaitika. The TIL therapy yakaratidza kushanda zvakanyanya. Mukati megore, anenge mapundu ose aAmai Y akanga anyangarika kana kuti kupera, ndokusara rimwe bedzi. Muna 2024, vanachiremba vakabvisa inenge hafu yechiropa chake, kusanganisira bundu rekupedzisira. Achimuka akaudzwa kuti muviri wake wakanga usina zviratidzo zvechirwere.
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