Myasthenia gravis-02

Li Ming's Myasthenia Gravis Kurapa Nyaya

Li Ming, mudzidzisi ane makore makumi matatu nemashanu, akatanga kuona zviratidzo zve myasthenia gravis (MG) makore matatu apfuura. Pakutanga, akacherechedza ptosis (kurembera kwemaziso) uye kutadza kutaura, asi zviratidzo zvishoma nezvishoma zvakaenda kune kushaya simba kwetsandanyama, zvichiita kuti kunyange mabasa ezuva nezuva ave akaoma. Pasinei nekurapwa kwakasiyana-siyana, kusanganisira steroid uye immunosuppressants, zviratidzo zvake zvakaramba zvisingadzoreki.

Kuburikidza nechisumo cheshamwari, Li Ming akasvika pachipatara cheLu Daopei kuti atore chikamu mukuyedzwa kwekiriniki yeCAR-T. Chikwata chenyanzvi chakaita ongororo yakadzama yezviratidzo zvake ndokumugadzirira kurapwa kweCAR-T.

Kurapa Maitiro:

1. Gadziriro Yechikamu: Asati arapwa, Li Ming akawana kuongororwa kwehutano hwakakwana. Vanachiremba vakaparadzanisa masero eT kubva mumuviri wake uye vakaachinja murabhoritari kuratidza chimeric antigen receptors (CAR) yakanangana nemaantigen chaiwo ane chekuita nemyasthenia gravis.

2. Kuwedzera Kwesero: Masero akagadziridzwa eCAR-T akawedzerwa mu laboratori kuti ave nechokwadi chokuti nhamba yakakwana yekurapa.

3. Preconditioning Chemotherapy: Pamberi peCAR-T cell infusion, Li Ming akaita vhiki-refu chemotherapy regimen kuderedza nhamba ye lymphocytes iripo mumuviri wake, zvichiita nzvimbo iri nani kuti masero eCAR-T ashande zvakanaka.

4. CAR-T Cell Infusion: Mushure mekupedza chemotherapy, Li Ming akaiswa muchipatara kuti agamuchire CAR-T cell infusion. Iyi nzira yakaitwa pasi pekutariswa kwakanyanya kudzivirira zvinogona kuitika.

Kurapa Kunobuda:

1. Mhinduro Yenguva pfupi: Muvhiki yekutanga mushure mekuiswa, Li Ming akawana fivha yakapfava uye kuneta, maitiro anowanzoitika kwenguva pfupi kuCAR-T cell therapy. Vhiki mbiri gare gare, ptosis yake uye kuoma kutaura kwakavandudzika zvikuru, uye simba rake rakatanga kudzoka.

2. Kunatsiridza kwepakati petemu: Mwedzi miviri gare gare, zviratidzo zvaLi Ming zvakanga zvadzikira. Akakwanisa kutangazve mabasa ekudzidzisa akajairwa, basa rake rakanaka rakavandudzwa, uye hupenyu hwake hwakaratidza kukwidziridzwa kukuru.

3. Nguva Yakareba Migumisiro: Mwedzi mitatu mushure mekurapa, Li Ming akanga asingachavimbi nemishonga yapfuura. Ongororo dzekutevera dzakaratidza kuti immune system yake yaive muchimiro chakanaka, pasina mhedzisiro yakaoma yakaonekwa.

Kuburikidza neCAR-T cell therapy, Li Ming's myasthenia gravis yakadzorwa zvakanyanya. "Ndinotenda chaizvo kurapwa kweCAR-T uye timu yakazvipira yekurapa nekuedza kwavo," Li Ming akadaro achichema, achizunza ruoko rwachiremba paakabuda.