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Innovative Gene Therapy Inopa Tariro Itsva yeSickle Cell uye Thalassemia Varwere

Innovative Gene Therapy Inopa Tariro Itsva yeSickle Cell uye Thalassemia Varwere
FUCASO: Iyo Yekuchinja Yakazara-Munhu BCMA CAR-T Therapy ine Isingaenzaniswi Kubudirira uye Kuchengetedzeka.

FUCASO: Iyo Yekuchinja Yakazara-Munhu BCMA CAR-T Therapy ine Isingaenzaniswi Kubudirira uye Kuchengetedzeka.
Optic Nerve Injury-03

Optic Nerve Injury-03
Optic Nerve Injury-02

Optic Nerve Injury-02
Optic Nerve Injury-01

Optic Nerve Injury-01
Metastatic melanoma-04

Metastatic melanoma-04
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Kenza yeOvarian-03
Ocular melanoma (pakutanga), inoteverwa nemetastatic chiropa tumors-02

Ocular melanoma (pakutanga), inoteverwa nemetastatic chiropa tumors-02
Yepamusoro nhanho IV colorectal cancer-01

Yepamusoro nhanho IV colorectal cancer-01
High-giredhi kenza yeprostate inoperekedzwa neakawanda mapfupa metastases-05

High-giredhi kenza yeprostate inoperekedzwa neakawanda mapfupa metastases-05
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FUCASO: Iyo Yekuchinja Yakazara-Munhu BCMA CAR-T Therapy ine Isingaenzaniswi Kubudirira uye Kuchengetedzeka.

FUCASO ishanduko yeBCMA-yakanangana neCAR-T kurapa neIASO BIO, inopa kushanda kusingaenzaniswi uye kuchengetedzeka kwekudzokazve kana kuramba akawanda myeloma. Iine mareti ekupindura akakwira, kuregererwa kwakasimba, uye chimiro chekuchengetedza chakasimba, FUCASO inopa tariro nyowani kuvarwere uye inoisa mwero mutsva muCAR-T kurapwa.

    Taura nesu
    product details
    Mabhenefiti Akakosha eFUCASO
    Kubudirira Kwechipatara

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    FUCASO, yakagadziridzwa neNanjing IASO Biotechnology, chirongwa chinoputsa CAR-T chakagadzirirwa kunanga B-cell maturation antigen (BCMA). Mushonga uyu unomira pachena nekuda kwekushanda kwayo kusingaenzaniswi kwekiriniki uye kuchengetedzeka chimiro, ichipa tariro nyowani kune varwere vane kudzokazve kana refractory multiple myeloma (r/rMM). Yakatenderwa neNational Medical Products Administration (NMPA) muna Chikumi 30, 2023, FUCASO yakatoratidza budiriro yakakosha mumakiriniki ekunyorera.

    High Response Rates: FUCASO inozvitutumadza mwero weKupindura Kwese (ORR) we98.9% uye Yakazara Mhinduro (CR) mwero we82.4%, wakakwira zvakanyanya kupfuura mamwe marapirwo aripo.

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    Durable Remission: Varwere vanobatwa neFUCASO vakaratidza mwedzi we12 Progression-Free Survival (PFS) chiyero che85.5%, zvichiratidza kuregererwa kwenguva refu uye kuvandudzwa kwehupenyu.

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    Safety Profile: Ne ≥3 giredhi Cytokine Release Syndrome (CRS) inoitika mu1% chete yevarwere uye hapana nyaya dzakataurwa dze ≥3 giredhi Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS), FUCASO inopa yakachengeteka kurapwa sarudzo kana ichienzaniswa nedzimwe CAR-T marapirwo. .

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    Mutengo-Kubudirira: Kurapa kweFUCASO kunodhura zvakanyanya kudarika marapirwo akafanana anowanikwa muUnited States, zvichiita kuti ive sarudzo inoshanda kune huwandu hwakawanda hwevarwere.

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    Global Reach: IASO BIO yakagadzira nzvimbo yekurapa yakakwana muChina, inokwanisa kushandira varwere kubva pasirese nesevhisi dzakabatanidzwa kubva pakubvunzana kusvika pakurapwa.

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    Murwere wekutanga akarapwa neFUCASO akawana makore mashanu ekupona pasina kenza, chiitiko chinoshamisa kana chichienzaniswa neyepakati Progression-Free Survival (PFS) yemwedzi 2.9 chete nekuchengetwa kwakajairwa. Izvi zvinoratidzira kugona kweFUCASO kushandura mamiriro ekurapa kune akawanda myeloma.

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