Yepamusoro nhanho IV colorectal cancer-01
Murwere ane makore makumi mana nemashanu ekuberekwa akaonekwa kuti ane chirwere chechirwere chegomarara chepamusoro IV muna Ndira 2023. Pakutanga, vanachiremba vakakurudzira nzira yakazara ye chemoradiotherapy. Nekudaro, nekuda kwekunyanya kuita neurotoxicity, kusanganisira paresthesia uye kushaya simba kwemakumbo zvichitevera chemotherapy, murwere akasarudza kurega imwe chemotherapy.
Sezvineiwo, murwere akasangana nematanho ekutsvaga ekuyedzwa kwekiriniki yeautologous tumor-infiltrating lymphocyte (TIL) kurapwa uye akashinga kusarudza kutora chikamu muyedzo. Mukutanga kwaKubvumbi 2023, murwere akagamuchira TIL cell infusion uye akazoitwa PD-1 monoclonal antibody immunotherapy zvinoenderana neprotocol yekuedzwa mumwedzi miviri yakatevera.
Mushure mekurapwa, murwere akashuma kuvandudzwa kukuru kwezviratidzo zvegastrointestinal uye kupora kwakanaka kwekuita basa. Yekutanga yakazara-muviri CT scan mushure mekuiswa kwakaratidza kuderedzwa kwebundu mutoro, kunyanya muchiropa uye peritoneal maronda. Sezvo kurapwa kwakaenderera mberi, kusimba kwemuviri wemurwere uye hupenyu hwehupenyu hwakavandudzika zvishoma nezvishoma.
Pakazosvika mwedzi wechitatu wekurapwa, kuongororwa kwakaratidza kuenderera mberi kwebundu shrinkage. Muviri-wese PET-CT scan yakaratidza yakadzikira zvakanyanya metabolic chiitiko mune metastatic maronda, uye mamwe maronda achinyangarika zvachose. Kubva pari zvino, kutevera kwemwedzi nemwedzi kunoratidza bundu rinoramba rakagadzikana pasina maronda matsva kana zviratidzo zvekudzokazve.
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