Khansara ya m'mawere-03

Mayi K, mayi wazaka 55 wolemera kwambiri anakakhala kunja, anakumana ndi khansa mwadzidzidzi. Zaka zitatu zapitazo, adakumana ndi kusapeza bwino komanso kutupa m'mimba mwake, komanso kuchepa kwa chidwi. Atamuyeza pachipatala china, anamupeza ndi khansa ya m’chiberekero cha chigawo IV. Chifukwa cha siteji yapamwamba komanso zotupa zambiri zomwe zimapezeka pakutsegula pamimba, kuchotsedwa kwa opaleshoni sikunali kotheka, kusiya chemotherapy ngati njira yokhayo.

Pambuyo pa opaleshoni, cholembera CA125 mu seramu yake chinakwera kuchoka pa 1800 U/mL kufika pa 5000 U/mL. Kupitilira kwa chemotherapy kunawonetsa kuchita bwino pang'ono, pomwe CA125 idakweranso kupitilira 8000 U/mL miyezi isanu ndi umodzi pambuyo pake. Madokotala anauza banja lake kuti nthawi yake yotsala inali yochepa ndipo anawalangiza kukonzekera mwamaganizo. Ngakhale kuti anaphunzira kuopsa kwa matenda ake, Mayi K sanasonyeze kuti anali wokhumudwa. Asanataye mtima, ankafuna kuyesa immunotherapy.

Chaka chatha, Mayi K adachitidwa opareshoni yoyamba kuti atengere zitsanzo. Pambuyo pa miyezi iwiri yakukulira kwa ex vivo, ma TIL adabwezedwanso m'thupi lake. Anadwala malungo tsiku lomwe anamuika, lomwe linatha tsiku lotsatira, ndipo anamva bwino kwambiri. Tsopano, patatha miyezi isanu ndi umodzi ya chithandizo, milingo yake ya CA125 yakhalabe pansi pa 18 U/mL. Kuyerekeza kwa zithunzi za PET-CT kukuwonetsa kuti mwa zotupa 24 zoyambirira za metastatic m'thupi lake, imodzi yokha yatsala. M’mwezi wa Marichi chaka chino, Mayi K anachitidwa opaleshoni yachiŵiri kuti atengere zitsanzo.