Metastatic melanoma-04

Wodwala Bambo Li, wamwamuna wazaka 45, adayamba kumva kupweteka m'mimba kosalekeza komanso kuwonda koyambirira kwa Marichi 2022. Kupimidwa kotsatira pachipatala cham'deralo kunapangitsa kuti apezeke mu April 2022 ndi metastatic melanoma. Ngakhale kuti anayesa chithandizo chamankhwala cha masiku angapo, kuphatikizapo opaleshoni, chithandizo cha radiotherapy, ndi mankhwala amphamvu, matenda ake anapitirizabe kuipiraipira, ndipo zotupa zinafalikira kuchiŵindi ndi m’mapapu.

Atalephera kugwiritsa ntchito njira zochiritsira zokhazikika, Bambo Li adafufuza njira zina zochiritsira mu Disembala 2022 atalandira upangiri wamankhwala. Atakambirana mozama ndikufufuza, adaganiza zoyesa njira yatsopano yopangira ma immunotherapy yotchedwa Tumor-Infiltrating Lymphocyte (TILs) therapy.

Njira ya TILs Therapy:

1. Kuchotsa Zitsanzo za Chotupa: Mu Januwale 2023, Bambo Li anachitidwa opaleshoni yaing’ono kuti achotse mbali ina ya chotupacho.

2. Kukula kwa Lymphocyte: Mu labotale, ofufuza anapatula Tumor-Infiltrating Lymphocytes (TILs) kuchokera ku chotupa chochotsedwa. Ma lymphocyte awa adakulitsidwa kangapo mu vitro kuti afikire kuchuluka komwe kumafunikira chithandizo.

3. Kukonzekera kwa Chemotherapy: Asanayambe kulowetsedwa kwa maselo a TILs, Bambo Li adalandira chithandizo chamankhwala kwa nthawi kuti achepetse chiwerengero cha ma lymphocyte omwe alipo m'thupi lake, kupanga malo a maselo a TILs omwe angolowetsedwa kumene.

4. TILs Cell Infusion: Mu Marichi 2023, maselo owonjezera a TILs adalowetsedwanso m'thupi la Bambo Li kudzera m'mitsempha.

5. Chithandizo Chothandizira: Pofuna kupititsa patsogolo ntchito za TILs, Bambo Li adalandiranso majekeseni angapo a Interleukin-2 (IL-2).

M’miyezi ingapo pambuyo pa chithandizocho, mkhalidwe wa Bambo Li unasintha kwambiri. Zotupazo zinachepa kwambiri, ndipo zotupa za metastatic zinasonyeza kupumula pang’ono. Kutsatira mu June 2023 kunawonetsa kutha kwa zotupa m'chiwindi ndi mapapo. Thanzi la Bambo Li linayamba kusintha pang’onopang’ono, kulemera kwawo kunabwerera, ndipo ululu wawo wa m’mimba unachepa.

"Nditadziwa za matenda anga, ndinamva ngati dziko lonse likuwonongeka. Nditalandira chithandizo chamankhwala chosagwira ntchito kangapo, ndinali nditatsala pang'ono kutaya chiyembekezo. Mwamwayi, ndinakumana ndi chithandizo cha TILs, chomwe sichinangopulumutsa moyo wanga komanso chinabwezeretsa chiyembekezo changa chamtsogolo. .Ndikuthokoza madotolo ndi ofufuza onse amene anandithandiza Ndi khama lanu lomwe landipatsa moyo watsopano ndikukhulupirira kuti chithandizochi chingathandize odwala ambiri ngati ine kuthana ndi khansa ndikulandiranso moyo wathanzi.