Chichewa
English French German Portuguese Spanish Russian Japanese Korean Arabic Irish Greek Turkish Italian Danish Romanian Indonesian Czech Afrikaans Swedish Polish Basque Catalan Esperanto Hindi Lao Albanian Amharic Armenian Azerbaijani Belarusian Bengali Bosnian Bulgarian Cebuano Chichewa Corsican Croatian Dutch Estonian Filipino Finnish Frisian Galician Georgian Gujarati Haitian Hausa Hawaiian Hebrew Hmong Hungarian Icelandic Igbo Javanese Kannada Kazakh Khmer Kurdish Kyrgyz Latin Latvian Lithuanian Luxembou.. Macedonian Malagasy Malay Malayalam Maltese Maori Marathi Mongolian Burmese Nepali Norwegian Pashto Persian Punjabi Serbian Sesotho Sinhala Slovak Slovenian Somali Samoan Scots Gaelic Shona Sindhi Sundanese Swahili Tajik Tamil Telugu Thai Ukrainian Urdu Uzbek Vietnamese Welsh Xhosa Yiddish Yoruba Zulu Kinyarwanda Tatar Oriya Turkmen Uyghur
Leave Your Message
Zogulitsa Magulu
Zamgululi
Innovative Gene Therapy Imapereka Chiyembekezo Chatsopano kwa Odwala Sickle Cell ndi Thalassemia

Innovative Gene Therapy Imapereka Chiyembekezo Chatsopano kwa Odwala Sickle Cell ndi Thalassemia
FUCASO: Therapy ya Revolutionary Fully-Human BCMA CAR-T yokhala ndi Kuchita bwino komanso Chitetezo

FUCASO: Therapy ya Revolutionary Fully-Human BCMA CAR-T yokhala ndi Kuchita bwino komanso Chitetezo
Kuvulala kwa Mitsempha ya Optic-03

Kuvulala kwa Mitsempha ya Optic-03
Kuvulala kwa Mitsempha ya Optic-02

Kuvulala kwa Mitsempha ya Optic-02
Kuvulala kwa Mitsempha ya Optic-01

Kuvulala kwa Mitsempha ya Optic-01
Metastatic melanoma-04

Metastatic melanoma-04
Khansara ya m'mawere-03

Khansara ya m'mawere-03
Ocular melanoma (poyamba), yotsatiridwa ndi zotupa za chiwindi za metastatic-02

Ocular melanoma (poyamba), yotsatiridwa ndi zotupa za chiwindi za metastatic-02
Advanced stage IV colorectal cancer-01

Gawo la IV colorectal cancer-01
Khansara ya prostate yapamwamba kwambiri yomwe imatsagana ndi mafupa angapo a metastases-05

Khansara ya prostate yapamwamba kwambiri yomwe imatsagana ndi mafupa angapo a metastases-05
Chithunzi 1.png
Kusintha kwa majini ndi chithandizo cha thalassemia (2) Image[23].jpg
Kusintha kwa majini ndi chithandizo cha thalassemia (3) Image[23].jpg
Kusintha kwa majini ndi chithandizo cha thalassemia (24) Image[23].jpg
Chithunzi 1.png
Kusintha kwa majini ndi chithandizo cha thalassemia (2) Image[23].jpg
Kusintha kwa majini ndi chithandizo cha thalassemia (3) Image[23].jpg
Kusintha kwa majini ndi chithandizo cha thalassemia (24) Image[23].jpg

Innovative Gene Therapy Imapereka Chiyembekezo Chatsopano kwa Odwala Sickle Cell ndi Thalassemia

BRL-101, ikuyimira kupita patsogolo kwakukulu pamankhwala a sickle cell disease (SCD) kudzera muukadaulo wa CRISPR/Cas9 wosintha ma gene. Thandizo lamakonoli limapereka chiyembekezo chatsopano mwa kuonjezera kwambiri mlingo wa hemoglobin wa fetal (HbF), womwe ukhoza kusintha kwambiri zotsatira za odwala.

    Lumikizanani nafe
    tsatanetsatane wazinthu

    Innovative Gene Therapy Imapereka Chiyembekezo Chatsopano kwa Odwala Sickle Cell ndi Thalassemia

    Kusintha kwa majini ndi chithandizo cha thalassemia (12) Image[24].jpg Kusintha kwa majini ndi chithandizo cha thalassemia 3Image[24].jpg

    Pachitukuko chachikulu cha odwala omwe ali ndi matenda a sickle cell (SCD) ndi thalassemia, chithandizo chatsopano cha majini chikuwonetsa kupambana kodabwitsa. Chithandizochi, chomwe chimagwiritsa ntchito ukadaulo wapamwamba wosintha ma gene CRISPR/Cas9, awonetsa chiwopsezo cha 100% pamayesero azachipatala, ndikupereka chiyembekezo chatsopano kwa omwe akulimbana ndi matenda oopsawa.

    Thandizo, lopangidwa ndi nsanja ya ModiHSC®, limayang'ana mizu ya SCD ndi thalassemia. Pokonza bwino chowonjezera cha BCL11A mu tsinde la autologous hematopoietic stem and progenitor cell, chithandizochi chimathandiza kuti thupi lipange kuchuluka kwa fetal hemoglobin (HbF). Miyezo yokwera ya HbF yasonyezedwa kuti ikulimbana ndi zotsatira zowononga za sickle hemoglobin (HbS) ndi kuchepetsa zizindikiro za SCD ndi thalassemia, kuphatikizapo kupewa matenda a vaso-occlusive ndi kuchepetsa kuchepa kwa magazi m'thupi.

    1].jpg         2.jpg

    BIOOCUS, yemwe ndi wotsogola pantchito ya gene therapy, mogwirizana ndi Chipatala cha Lu Daopei, athandizira kwambiri kubweretsa chithandizo chamakono kwa odwala. 

    Kupambana kwachipatala kwachipatala sikungafanane, ndi odwala 15 omwe adalandira chithandizo mpaka pano, onse akulandira chikhululukiro chathunthu komanso kusintha kwakukulu kwa moyo wawo. Kuchiritsa kwa 100% kumeneku ndi gawo lofunikira kwambiri polimbana ndi SCD ndi thalassemia.

     

    Thandizoli ladziwika padziko lonse lapansi, ndipo akatswiri padziko lonse lapansi amaliyamikira ngati njira yothandiza kwambiri pochiza matenda obwera chifukwa cha majini. Sichidziwika kokha chifukwa cha mphamvu zake komanso chifukwa cha mtengo wake. Mosiyana ndi mankhwala ena amtundu, omwe amatha kukhala okwera mtengo kwambiri, chithandizochi chimapereka njira yofikira pamitengo, zomwe zimapangitsa kukhala njira yabwino kwa odwala ambiri.

    Pankhani ina yochititsa chidwi, wodwala wazaka 12 yemwe anali ndi vuto la vaso-occlusive mobwerezabwereza komanso kuchepa kwa magazi m'thupi la hemolytic kutha kwa zizindikiro pambuyo pa chithandizo cha jini. Mlanduwu, pakati pa ena, ukuwonetsa kuthekera kosinthika kwa chithandizo cha odwala a SCD ndi thalassemia padziko lonse lapansi.

    4.jpg     3.jpg

    Pamene BIOOCUS ikupitiliza kukulitsa kupezeka kwa mankhwalawa, kuphatikiza mayeso azachipatala omwe akubwera ku China, tsogolo likuwoneka ngati labwino kwa omwe akhudzidwa ndi matenda ovutawa. Mothandizidwa ndi Chipatala cha Lu Daopei, chithandizochi chakhazikitsidwa kuti chifotokozenso mulingo wa chisamaliro cha SCD ndi thalassemia, kupereka moyo watsopano kwa odwala osawerengeka.

    Ngati inu kapena okondedwa anu akukhudzidwa ndi matenda a sickle cell kapena thalassemia ndipo mukufuna kudziwa chithandizo chamakonochi, tikukupemphani kuti mutilankhule. Gulu lathu lakonzeka kukupatsirani chithandizo ndi chidziwitso chomwe mukufuna kuti mupange zisankho zodziwika bwino zaulendo wanu wazachipatala.