Gawo la IV colorectal cancer-01

Wodwalayo ndi mwamuna wazaka 45 yemwe adapezeka ndi khansa yamtundu wa IV mu January 2023. Poyambirira, madokotala adalimbikitsa njira yonse ya chemoradiotherapy. Komabe, chifukwa cha kuopsa kwa neurotoxicity, kuphatikizapo paresthesia ndi kufooka kwa miyendo pambuyo pa chemotherapy, wodwalayo anaganiza zosiya kugwiritsira ntchito mankhwala a chemoradiotherapy.

Mwamwayi, wodwalayo anakumana ndi njira zolembera anthu kuti ayesedwe kuchipatala cha autologous tumor-infiltrating lymphocyte (TIL) therapy ndipo adasankha mwachangu kutenga nawo mbali mu mayesero. Kumayambiriro kwa Epulo 2023, wodwalayo adalandira kulowetsedwa kwa cell ya TIL ndipo pambuyo pake adalandira PD-1 monoclonal antibody immunotherapy malinga ndi ndondomeko yoyeserera miyezi iwiri yotsatira.

Pambuyo pa chithandizo, wodwalayo adanenanso kusintha kwakukulu kwa zizindikiro za m'mimba komanso kuchira bwino kwa matumbo. Kujambula koyamba kwa thupi lonse pambuyo pa kulowetsedwa kunasonyeza kuchepa kwa chotupa, makamaka m'chiwindi ndi zilonda zam'mimba. Pamene chithandizo chinapitirira, thupi la wodwalayo limakhala lolimba komanso umoyo wabwino pang'onopang'ono.

Pofika mwezi wachitatu wa chithandizo, zowunikiranso zikuwonetsa kuti chotupacho chikuchepa. Kujambula kwa thupi lonse kwa PET-CT kunawonetsa kuchepa kwambiri kwa kagayidwe kachakudya m'mabala a metastatic, ndi zotupa zina kutha. Pofika pano, kutsatiridwa kwa mwezi ndi mwezi kumasonyeza kuti chotupacho chimakhala chokhazikika popanda zilonda zatsopano kapena zizindikiro zobwereza.