Nnukwu ọrịa leukemia Lymphoblastic (T-ALL) -09

Otu nwa akwụkwọ mahadum aha ya bụ Mengmeng si Yanjiao, Guizhou, nwetara ọgwụgwọ dị mma na ụlọ ọgwụ Ludaopei.

Mengmeng, nwanyị, dị afọ 21, gosipụtara n'ihu ụlọọgwụ anyị na June 22, 2021, na ike ọgwụgwụ na-adịgide adịgide. Nnwale oge ọbara gosipụtara WBC 479×10^9/L. Nyocha ụmị ọkpụkpụ ndị ọzọ akwadoro nnukwu ọrịa leukemia lymphoblastic (T-cell subtype). Ọ nwetara usoro ọgwụgwọ chemotherapy abụọ, mana ọrịa leukemia nọgidere na-anabataghị ya, yana MRD (ọrịa obere ihe fọdụrụnụ) na 56.01%, yana o nwekwara itinye aka na sistemụ akwara ọbara leukemia.

N'August 13, a nakọtara lymphocytes autologous ma nyekwa ọgwụgwọ chemotherapy. N'August 30, Mengmeng nwetara infusion cell CD7 CAR-T. Izu abụọ mgbe infusion gasịrị, nyocha nke ụmị ọkpụkpụ gosipụtara mgbaghara zuru oke, MRD negativity, na ịchịkwa ọrịa leukemia nke etiti ụbụrụ. Ọ nwetara mmeghachi omume cytokine release syndrome (CRS) ọkwa 1 na enweghị mmeghachi omume ọjọọ nke sistemu ụjọ etiti.