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Cov txiaj ntsig tau txais txiaj ntsig ntawm CD7 CAR-T Kev Kho Mob Ua Ke Nrog Kev Hloov Thib Ob hauv Cov Neeg Mob T-ALL/LBL

Cov txiaj ntsig tau zoo ntawm CD7 C ...

$Lub Sijhawm Ua Tau Zoo ntawm CD19 CAR T-Cell Therapy hauv Kev Kho Mob Relapsed/Refractory Acute Lymphoblastic Leukemia$

Lub Sijhawm Ua Tau Zoo ntawm CD19 ...

Bioocus Advances Frontier nyob rau hauv Kev Kho Mob Pediatric Acute Lymphoblastic Leukemia

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Pioneering CAR-T Therapy hauv ...

Lub tswv yim CAR-T Cell Therapies Hloov Kho B Cell Malignancies

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Enhanced Antitumor Efficacy ntawm 4-1BB-raws li CD19 CAR-T Cells hauv Kev Kho B-ALL

Enhanced Antitumor Efficiency...

Lu Daopei Tsev Kho Mob Kev Kho Mob Tsawg-Dose CD19 CAR-T Qhia Tau Zoo Tshaj Plaws hauv B-ALL Cov Neeg Mob

Lu Daopei Tsev Kho Mob Low-Do...

Novel Promoter Strategy Enh...

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Kev Tshaj Tawm Ua Ntej Hauv Ntuj Killer (NK) Cells Tshaj 50 Xyoo

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Enhanced Antitumor Efficacy ntawm 4-1BB-raws li CD19 CAR-T Cells hauv Kev Kho B-ALL

2024-08-01 IB

Hauv kev tshawb fawb soj ntsuam tseem ceeb ua los ntawm Lu Daopei Tsev Kho Mob thiab Lu Daopei Lub Tsev Kho Mob Hematology, cov kws tshawb fawb tau pom tias 4-1BB-raws li CD19 CAR-T hlwb muab kev cog lus rau lwm cov CD28-based CAR-T hlwb rau kev kho mob rov qab los yog refractory. B cell mob lymphoblastic leukemia (r/r B-ALL). Txoj kev tshawb no, suav nrog cov kev tshawb fawb soj ntsuam ua ntej thiab kev tshawb fawb soj ntsuam, pom tias 4-1BB CAR-T hlwb tsis tsuas yog muab cov tshuaj tiv thaiv kab mob siab dua tab sis kuj tseem ua rau muaj kev pheej hmoo ntev rau cov neeg mob piv rau lawv cov CD28 counterparts.

Lub Tsev Kho Mob Lu Daopei cov kws tshawb fawb tau ua tib zoo sib piv qhov kev ua tau zoo ntawm ob hom CAR-T cell. Lawv tau tshawb pom tias, nyob rau hauv tib txoj kev tsim khoom, 4-1BB CAR-T hlwb muaj cov nyhuv antitumor ntau dua ntawm cov koob tshuaj qis dua thiab ua rau muaj kev cuam tshuam tsawg dua li CD28 CAR-T hlwb. Cov txiaj ntsig ntawm txoj kev tshawb fawb qhia tau hais tias 4-1BB-raws li kev kho mob CAR-T tuaj yeem muab kev kho mob zoo dua thiab muaj kev nyab xeeb dua rau cov neeg mob uas muaj r / r B-ALL .

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Cov kev tshawb pom no qhia txog kev cog lus ntawm Lub Tsev Kho Mob Lu Daopei txhawm rau txhim kho hematology thiab immunotherapy, muab kev cia siab rau cov neeg mob uas tsis tau teb rau cov kev kho mob ib txwm muaj. Txoj kev tshawb no, uas tau ua raws li cov qauv kev coj ncaj ncees thiab tau txais kev pom zoo los ntawm Lu Daopei Tsev Kho Mob Ethics Committee, hais txog lub tsev kho mob lub luag haujlwm hauv kev ua cov kev tshawb fawb tshiab hauv CAR-T cell therapies.

Nrog rau qhov kev ua tiav no, Lu Daopei Lub Tsev Haujlwm ntawm Hematology txuas ntxiv ua tus thawj coj tshiab hauv kev tshawb fawb txog kev kho mob, muab cov kev xaiv kho mob tshiab thiab txhim kho cov txiaj ntsig ntawm tus neeg mob. Qhov kev nce qib no yog ib qho pov thawj rau kev mob siab rau thiab kev txawj ntse ntawm Lu Daopei Tsev Kho Mob pab pawg kho mob thiab tshawb fawb.