Daim Ntawv Qhia Tag Nrho ntawm Kev Kho Mob Leukemia Groundbreaking
Indications ntawm CAR-T
●B-cell mob lymphoblastic leukemia
●Ntau myeloma
●Chronic lymphocytic leukemia
●Tsis yog Hodgkin lymphoma
●Diffuse loj B-cell lymphoma
●SLE (Systemic Lupus Erythematosus)
●Myasthenia gravis
●Lwm yam kab mob autoimmune
Kev ua tau zoo ntawm CAR-T kev kho mob
Indications rau CD19+20CAR-T:Cov neeg mob uas muaj B-cell tsis yog Hodgkin's lymphoma
Ib hlis CR tus nqi | Ib hlis PR tus nqi | Ib hlis LOS YOG tus nqi | CRS≥3 | CRES ≥ 3 |
71.95% (59/82) | 25.6 (21/82) | 97.55 (80/82) | 12.19% (10/82) | 0 |
Indications rau CD19+22CAR-T:Kev kho mob ntawm CD19 relapsed thiab refractory mob B-lymphocytic leukemia cov neeg mob
Ib hlis CR tus nqi | Ib hlis PR tus nqi | Ib hlis LOS YOG tus nqi | CRS≥3 | CRES ≥ 3 |
92.1% (35/38) | 7.9% (3/38) | 100% (38/38) | 15.79% (6/38) | 0 |
Indications rau BCMACAR-T:Kev kho mob ntawm relapsed thiab refractory ntau myeloma
Ib hlis CR tus nqi | Ib hlis PR tus nqi | Ib hlis LOS YOG tus nqi | CRS≥3 | CRES ≥ 3 |
72.41% (21/29) | 27.59% (8/29) | 100% (29/29) | 6.9% (2/29) | 0 |
Peb Qhov Zoo
● Kev kho tus kheej: Txhua txoj kev kho CAR-T raug kho rau tus neeg mob, kom ntseeg tau cov txiaj ntsig kev kho mob zoo heev.
● Muaj ntau hom phiaj kev xaiv: Nrog rau ntau hom phiaj antigens, suav nrog CD7, CD19, CD20, CD22, thiab BCMA, peb cov khoom CAR-T muaj ntau yam tsis sib xws hauv kev kho ntau yam hematological malignancies thiab kab mob autoimmune.
● Pov thawj Clinical Success: Peb cov kev kho mob CAR-T tau pom tias muaj txiaj ntsig tshwj xeeb thoob plaws ntau qhov chaw kho mob, nrog rau cov txiaj ntsig zoo thiab kev nyab xeeb, txhawb nqa peb txoj haujlwm ua tus thawj coj hauv kev tiv thaiv kab mob.
● Tus nqi-zoo: Peb muab kev sib tw nrog cov kev kho mob zoo tshaj ntawm tus nqi siv tau ntau dua piv rau lwm cov khoom siv CAR-T hauv khw.
● Txiav-Edge Technology: Siv cov kev nce qib tshiab kawg hauv kev tsim noob caj noob ces, peb cov kev kho mob CAR-T embody lub neej yav tom ntej ntawm kev mob qog noj ntshav thiab kev kho kab mob autoimmune.
● Kev Pabcuam Kws Kho Mob: Peb pab pawg kws kho mob thiab cov kws tshawb fawb tau paub txog muab kev saib xyuas zoo los ntawm kev sab laj thawj zaug los ntawm kev tswj hwm kev kho mob thiab kev soj ntsuam.
CAR-T hlwb tam sim no tau lees paub dav dav rau lawv cov kev ua tau zoo hauv cov neeg mob uas tsis tau teb rau cov kev kho mob ib txwm muaj xws li tshuaj kho mob lossis hloov pob txha pob txha. Lub zej zog kho mob thoob ntiaj teb lees paub qhov muaj peev xwm ntawm CAR-T txoj kev kho hauv kev hloov pauv cov txiaj ntsig ntawm tus neeg mob.
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