Mob Lymphoblastic Leukemia (T-ALL)-09

Ib tug menyuam kawm ntawv hauv tsev kawm ntawv npe hu ua Mengmeng los ntawm Yanjiao, Guizhou, tau txais kev kho mob zoo hauv Tsev Kho Mob Ludaopei.

Mengmeng, poj niam, 21 xyoo, tau nthuav tawm rau peb lub tsev kho mob sab nraud thaum Lub Rau Hli 22, 2021, nrog kev qaug zog tsis tu ncua. Kev kuaj ntshav niaj hnub pom WBC 479 × 10^9 / L. Kev kuaj mob pob txha ntxiv tau lees paub tias mob lymphoblastic leukemia (T-cell subtype). Nws tau txais ob lub voj voog ntawm kev siv tshuaj khomob, tab sis leukemia tseem tsis teb, nrog MRD (cov kab mob tsawg kawg nkaus) ntawm 56.01%, thiab nws kuj muaj kev cuam tshuam hauv nruab nrab ntawm lub paj hlwb leukemia.

Thaum Lub Yim Hli 13, autologous lymphocytes tau sau thiab siv tshuaj kho mob. Lub Yim Hli 30, Mengmeng tau txais CD7 CAR-T cell infusion. Ob lub lis piam tom qab infusion, kev kuaj mob pob txha pom tau tias ua tiav kev tshem tawm, MRD tsis zoo, thiab kev tswj hwm ntawm cov hlab ntsha hauv nruab nrab ntawm cov hlab ntsha. Nws tau ntsib qib 1 cytokine release syndrome (CRS) cov tshuaj tiv thaiv uas tsis muaj kev cuam tshuam hauv nruab nrab ntawm lub paj hlwb.