Mob Lymphoblastic Leukemia (T-ALL)-08

Yesheng los ntawm Fujian hais tias, "Yog tias kuv tau paub txog CAR-T ntawm Ludaopei, kuv yuav tuaj ntxov."

Thaum lub Cuaj Hlis 2017, Yesheng tau tsim cov pob khaus ntawm lub ntsej muag, uas maj mam kis mus rau hauv thaj ua rau thaj. Thaum Lub Ob Hlis 28, 2018, kev kuaj mob pob txha tau lees paub tias "mob T-cell lymphoblastic leukemia" tom qab ntau chav kawm ntawm kev kho mob, nrog kev kuaj xyuas tsis zoo. Tag nrho cov tshuaj tau tso tseg thaum Lub Rau Hli 2019.

Thaum lub Tsib Hlis 2021, Yesheng nthuav tawm nrog cov neeg coob coob hauv thaj tsam ntawm qhov ncauj-pharyngeal thiab lub caj dab loj dua. Cov pob txha pob txha rov kuaj xyuas tau pom tias muaj kev rov ua tiav ntawm leukemia. Thaum Lub Tsib Hlis 28, Yesheng tau raug xa mus rau Lub Tsev Haujlwm Saib Xyuas Hematology Thib Ob ntawm Ludaopei Tsev Kho Mob rau kev nkag. Tom qab kev ntsuam xyuas tiav, qhov kev kuaj mob tau hloov kho rau "mob leukemia (T / myeloid biphenotypic).

Ib lub voj voog ntawm kev siv tshuaj khomob tsis ua rau kev tso tawm hauv cov pob txha. Thaum Lub Xya Hli 27, Yesheng tau txais CD7 CAR-T cell infusion, ua raws li kev kho mob ua ke nrog autologous CD7 CAR-T cell therapy. Kaum tsib hnub tom qab kev txhaj tshuaj, kev kuaj mob pob txha pom tau tias muaj kab mob tsis zoo, nrog rau qib 1 cytokine release syndrome (CRS) cov tshuaj tiv thaiv thiab tsis muaj kev cuam tshuam hauv nruab nrab ntawm lub paj hlwb.