ʻO Lymphoma B-cell nui (DLBCL)

ʻO ka mea maʻi, he wahine kūpaʻa kokoke i 80 mau makahiki, ua alo wiwo ʻole i ka maʻi o ka Diffuse Large B-cell Lymphoma (DLBCL), e hōʻike ana i ka wiwo ʻole i kāna kaua ʻana i kēia ʻano maʻi maʻi ʻino.

ʻOiai ʻo kona mau makahiki ʻelemakule, ua hoʻomau ʻo ia i ka paʻa e lanakila i nā pilikia i loaʻa mai i kona kūlana. Eia naʻe, i loko o ʻeono mahina ma hope o ka loaʻa ʻana o ke kala ʻana me ka lāʻau lapaʻau mua, ua ʻike ʻo ia i ka hoʻihoʻi hou ʻana, e hōʻike ana i ke ʻano koʻikoʻi o kāna maʻi. ʻOiai ʻo nā hoʻāʻo he nui me nā lāʻau lapaʻau ʻelua a me ke kolu, ua hōʻike ʻia kona maʻi maʻi i ke kūpaʻa paʻakikī, e hōʻike ana i kahi luʻi nui no kāna hui lapaʻau.

I ka ʻike ʻana i ka wikiwiki o kona kūlana, ua hoʻomaka ka hui lapaʻau i kahi ʻimi e ʻimi i nā koho lapaʻau ʻē aʻe. Ua kākau ʻia ka mea maʻi i loko o kahi hoʻokolohua lapaʻau e noiʻi ana i ka CD19+22 CAR-T cell therapy, kahi ala ʻokiʻoki e hoʻohana ana i nā pūnaewele T i hoʻopaʻa ʻia i ka genetically e hoʻopaʻa i nā cell cancer e hōʻike ana i nā antigens kikoʻī.

ʻAʻohe mea pōkole o nā hopena. Hoʻokahi mahina ma hope o ka hoʻokomo ʻia ʻana o nā cell CD19+22 CAR-T, ua loaʻa i ka mea maʻi ke kala piha. ʻAʻole i hoʻōki wale kēia hopena i ka piʻi ʻana o kāna maʻi akā ua alakaʻi pū ʻia i ka hoʻopau kūleʻa ʻana o nā maʻi kanesa, e hōʻailona ana i kahi manawa koʻikoʻi i kāna huakaʻi lapaʻau.

I loko o ke kaʻina hana paʻakikī, hāʻawi ka hui lapaʻau i ke kākoʻo a me ka mālama ʻole i ka mea maʻi. Mai ka nānā pono ʻana i kāna pane ʻana i ka lāʻau lapaʻau i ka hoʻokele ʻana i nā hanana pōʻino, ua hōʻoia lākou i kona ola maikaʻi ʻana i ka mea nui.

Ma ka noʻonoʻo ʻana i kāna ʻike, ua hōʻike ka mea maʻi i ka mahalo nui no ka mālama aloha i loaʻa iā ia. "ʻO ka hoʻolaʻa a me ka ʻike o kaʻu hui lapaʻau he ʻokoʻa maoli," wahi āna. "ʻO kā lākou hana pilikino i ka mālama ʻana i hāʻawi mai iaʻu i ka manaʻolana i ka wā e pono ai iaʻu."

ʻO ka hopena kūleʻa o ka CD19+22 CAR-T cell therapy i ka loaʻa ʻana o ke kala piha e hōʻike ana i kona hiki ke koho i kahi koho lapaʻau no nā maʻi DLBCL refractory. He hōʻike kēia hihia i ka mana o nā lāʻau lapaʻau hou a me nā lāʻau lapaʻau pilikino i ka mālama ʻana i nā maʻi maʻi maʻi paʻakikī, ʻoi loa i nā poʻe maʻi ʻelemakule e like me kēia wahine wiwo ʻole.

Ma mua & 1 mahina ma hope o ka infusion