Leukemia Lymphoblastic Acute (T-ALL)-09

Ua loaʻa i kahi haumāna kulanui ʻo Mengmeng mai Yanjiao, Guizhou, ka mālama maikaʻi ʻana ma ka Halemai Ludaopei.

ʻO Mengmeng, wahine, 21 mau makahiki, i hōʻike ʻia i ko mākou keʻena maʻi maʻi ma Iune 22, 2021, me ka luhi mau. Hōʻike ka hoʻāʻo maʻamau i ke koko WBC 479×10^9/L. Ua hōʻoia ʻia ka maʻi maʻi lymphoblastic acute (T-cell subtype). Ua loaʻa ʻo ia i ʻelua mau pōʻai o ka chemotherapy, akā ʻaʻole i pane ʻia ka maʻi leukemia, me ka MRD (maʻi koena liʻiliʻi) ma 56.01%, a ua loaʻa pū ʻo ia i ka maʻi maʻi maʻi maʻi waena.

Ma ʻAukake 13, ua hōʻiliʻili ʻia nā lymphocytes autologous a ua lawelawe ʻia ka chemotherapy. Ma ʻAukake 30, loaʻa iā Mengmeng ka CD7 CAR-T cell infusion. ʻElua pule ma hope o ka hoʻokomo ʻana, ua hōʻike ʻia ka hoʻokolokolo ʻana o ka iwi iwi i ke kala piha, MRD negativity, a me ka hoʻomalu ʻana i ka maʻi maʻi maʻi pūpū. Ua ʻike ʻo ia i ka hopena o ka cytokine release syndrome (CRS) papa 1 me ka ʻole o nā hopena ʻino o ke kikowaena.