Bioocus yana Ci gaban gaba a cikin Maganin Cutar sankarar mahaifa mai Mugun Lymphoblastic
Wani muhimmin abu mai mahimmanci a fagen CAR-T, wanda aka nuna ta kwanan nan na wani bincike mai zurfi wanda Dr. Chunrong Tong ya jagoranta a asibitin Lu Daopei. Binciken, mai suna "Kwarewa da Kalubale na Tsarin Halitta na Biyu CD19 CAR-T Cell Therapy in Pediatric Acute Lymphoblastic Leukemia," yana ba da cikakken bincike game da inganci da aminci na CD19 CAR-T na ƙarni na biyu a cikin maganin cutar sankarar mahaifa na yara. (ALL).
Wannan binciken yana nuna sabbin yuwuwar samfurin CAR-T na Bioocus wajen magance ɗayan mafi ƙalubalanci yanayin ilimin jini a cikin yara. Binciken ya yi bayani dalla-dalla game da sakamakon asibiti da aka lura a cikin marasa lafiya da suka sami wannan maganin, yana bayyana ƙimar gafara. Duk da haka, yana kuma gano ƙalubale masu mahimmanci, musamman ma kula da ciwo mai tsanani na cytokine saki (CRS) da neurotoxicity, wanda ya kasance mahimman wuraren mayar da hankali don inganta lafiyar haƙuri.
Maganin CAR-T na Bioocus, wanda aka nuna a cikin wannan binciken, yana ba da damar ƙira na ƙarni na biyu wanda ke haɓaka ayyukan T-cell akan ƙwayoyin kansa waɗanda ke bayyana antigen CD19. Wannan hanya tana da mahimmanci wajen shawo kan hanyoyin juriya da ake fuskanta sau da yawa a cikin sake dawowa ko rashin jin daɗin yara DUK lokuta. Sakamakon da aka gabatar a cikin wannan ɗaba'ar ba wai kawai yana nuna yuwuwar warkewa na samfurin CAR-T na Bioocus ba har ma yana jaddada mahimmancin ci gaba da ƙididdigewa da bincike na asibiti don ƙara inganta waɗannan hanyoyin kwantar da hankali.
Binciken Dokta Tong yana ba da gudummawar basira mai mahimmanci game da aikace-aikacen hanyoyin kwantar da hankali na CAR-T kuma ya dace da manufar Bioocus don ci gaba da maganin ciwon daji ta hanyar yanke-baki-baki na fasahar halittu. A matsayinsa na jagoran duniya a ci gaban CAR-T, Bioocus ya ci gaba da jajircewa wajen tura iyakokin abin da zai yiwu a cikin maganin cutar kansa, tare da babban burin inganta sakamakon haƙuri da ingancin rayuwa.
Yayin da Bioocus ya ci gaba da yin haɗin gwiwa tare da manyan cibiyoyin kiwon lafiya kamar asibitin Lu Daopei, mun ci gaba da sadaukar da kai don magance ƙalubalen da aka gano a cikin wannan binciken da kuma tace samfuran mu na CAR-T don haɓaka amincin su da inganci. Ƙullawarmu ga ƙwarewa da ƙirƙira yana tabbatar da cewa muna da matsayi mai kyau don jagorantar makomar maganin ciwon daji.