Myasthenia gravis-01
Labarin Maganin Myasthenia Gravis na Zhang Wei
Zhang Wei, injiniyan software mai shekaru 32, ya fara samun alamun cutar myasthenia gravis (MG) shekaru biyu da suka wuce. Da farko, yana da ptosis (faɗowar fatar ido) da hangen nesa, amma alamunsa sun tsananta a tsawon lokaci, wanda ya haifar da raunin tsoka wanda ya shafi aikinsa da rayuwar yau da kullum. Duk da shan jiyya daban-daban, ciki har da magungunan anticholinesterase, immunosuppressants, da immunoglobulin na ciki, alamunsa sun ci gaba kuma suna sake dawowa akai-akai.
Tare da magungunan gargajiya da ke nuna rashin tasiri, likitoci sun ba da shawarar cewa Zhang Wei ya gwada sabuwar hanyar magani: CAR-T cell far. Wannan sabuwar fasahar tana amfani da injiniyoyin halitta don gyara nasu ƙwayoyin T na majiyyaci, yana ba su damar yin niyya da kawar da ƙwayoyin da ba su da kyau da ke da alaƙa da cutar.
Bayan cikakken kimantawa, Zhang Wei an ga ya dace da maganin. Likitoci sun fara ware ƙwayoyin T daga jikinsa kuma sun canza su ta hanyar kwayoyin halitta tare da fadada su a cikin dakin gwaje-gwaje. Daga nan sai Zhang Wei ya yi amfani da ilimin chemotherapy don rage yawan adadin lymphocytes da ke cikin jikinsa, yana shirye-shiryen shigar da ƙwayoyin CAR-T. A ƙarshe, an sake shigar da ƙwayoyin CAR-T a cikin jikin Zhang Wei.
A lokacin farkon jiyya, Zhang Wei ya ɗan gaji, amma bayan makonni biyu, alamunsa sun fara inganta sosai. ptosis da blur hangen nesa sun ragu sosai, kuma ƙarfinsa ya dawo a hankali. Bayan wata daya, ingancin aikinsa ya inganta, kuma zai iya ci gaba da ayyukan yau da kullun. Watanni uku bayan jinya, alamun Zhang Wei sun kusan bace gaba daya, kuma baya bukatar magungunan da suka gabata. Binciken da aka yi a baya ya nuna cewa tsarin garkuwar jikin sa yana cikin yanayi mai kyau, ba tare da wata illa mai tsanani ba ko kuma alamun sake bullar cutar.
Ta hanyar jiyya na CAR-T, Zhang Wei's myasthenia gravis ya sami kulawa sosai, yana haɓaka ingancin rayuwarsa da iya aiki sosai. Wannan maganin yana ba da sabon bege ga yawancin marasa lafiya myasthenia gravis.
bayanin 2