Bjørn Simensen ---- Multiple Myeloma (IgG lambda) ISS-II

Taya murna! Wani majiyyaci daga Norway, Bjørn Simensen, tare da tsawon shekaru biyu na remission.

Bjørn Simensen mai shekaru 67 ya gabatar da shi ga asibiti a watan Satumba na 2017 tare da gunaguni na tari da ciwon kirji. A lokacin aikin sa, an same shi yana da myeloma da yawa (IgG lambda) ISS-II. Mai haƙuri ya karɓi hawan 4 na bortezomib, lenalidomide da dexamethasone chemotherapy. Buga zagayowar 4 sunadaran M ɗin sa bai kai 1g/l ba. Sannan mai haƙuri ya fita kulawar lenalidomide (10mg qdx3 makonni a kowane wata m) wanda ya ci gaba da shekaru 2 masu zuwa. Ya kasance ba shi da cuta har zuwa lokacin rani na 2021 lokacin da a lokacin tantancewar gafara an gano cewa ya haɓaka M protein (5g/l). An dakatar da Lenalidomide kuma an fara shi akan carfilzomib da daratumumab chemotherapy daga Oktoba zuwa Disamba 2021. Duk da haka, maganin chemotherapy bai yi tasiri ba kuma bayan-chemo BM MRD ya kasance tabbatacce.

An fara ganin Mista Bjørn Simensen a Asibitin Lu Daopei a ranar 14 ga Fabrairu 2022. BM MRD ɗin sa ya nuna 0.25 bisa ɗari na ƙwayoyin plasma mara kyau. IEF ya nuna furotin IgG da M shine 3 g/l. PET-CT Scan ya nuna karuwar shan jini a cikin gwajin jini musamman ma wanda ya dace wanda kuma ya kara girma akan jarrabawa. An gudanar da wani biopsy na jini wanda ya nuna mummunan ƙwayoyin plasma. An zaɓi mai haƙuri don maganin ƙwayar cuta ta CART. An yi preconditioning tare da fludarabine da cyclophosphamide na kwanaki 3. An shigar da Kwayoyin CAR-T a ranar 0 (4/3/2222). Adadin da aka bayar shine 0.5X10^6/kg. Bayan jiko, mai haƙuri yana da zazzabin neutropenia wanda aka sarrafa tare da maganin rigakafi na iv. Kumburi na dama a hankali ya ragu zuwa girman al'ada. A ranar 28 gwajin BM ya kasance mara kyau ga ƙwayoyin plasma. An sallami mai haƙuri daga Lu Daopei tare da kulawa akai-akai a cibiyar nazarin jini a birninsa.