M cutar sankarar bargo ta Lymphoblastic (T-ALL) -09

Wani dalibin jami'a mai suna Mengmeng daga Yanjiao, Guizhou, ya sami ingantaccen magani a asibitin Ludaopei.

Mengmeng, mace, 'yar shekara 21, an gabatar da ita ga asibitin mu na waje a ranar 22 ga Yuni, 2021, tare da ci gaba da gajiya. Gwajin jini na yau da kullun ya nuna WBC 479 × 10^9/L. Karin gwaje-gwajen kasusuwan kasusuwa sun tabbatar da cutar sankarar bargo ta lymphoblastic (T-cell subtype). An yi ta hawan keke biyu na chemotherapy, amma cutar sankarar bargo ta kasance ba ta da amsa, tare da MRD (cututtukan da ba a taɓa samu ba) a kashi 56.01%, kuma tana da haɗin gwiwar tsarin jijiya na tsakiya.

A ranar 13 ga Agusta, an tattara lymphocytes na autologous kuma an gudanar da maganin chemotherapy. A ranar 30 ga Agusta, Mengmeng ya sami jiko tantanin halitta CD7 CAR-T. Makonni biyu bayan jiko, gwajin kasusuwa na kasusuwa ya nuna cikakkiyar gafara, rashin lafiyar MRD, da kuma kula da cutar sankarar jini ta tsakiya. Ta fuskanci wani mataki na 1 cytokine release syndrome (CRS) ba tare da wani mummunan halayen tsarin juyayi na tsakiya ba.